Methanococcus maripaludis S2 Module 58 Residual: 0.49

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Summary

Residual: 0.49 Score: -10.1079 version: mmp_cmonkey_11_Oct_11

Members

MMP0050 riboflavin synthase, beta subunit (6,7-dimethyl-8-ribityllumazine synthase) (NCBI)

Details for MMP0050 - riboflavin synthase, beta subunit (6,7-dimethyl-8-ribityllumazine synthase) (NCBI)

GO Terms: GO:0009231, GO:0009349, GO:0004746

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0050

Tuberculist Genomic Region

MMP1135 Flavodoxin:Beta-lactamase-like (NCBI)

Details for MMP1135 - Flavodoxin:Beta-lactamase-like (NCBI)

GO Terms: GO:0010181, GO:0016491, GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1135

Tuberculist Genomic Region

MMP0051 Phosphoribosyl-ATP pyrophosphatase (NCBI)

Details for MMP0051 - Phosphoribosyl-ATP pyrophosphatase (NCBI)

GO Terms: GO:0000105, GO:0004636

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0051

Tuberculist Genomic Region

MMP1136 Rubrerythrin (NCBI)

Details for MMP1136 - Rubrerythrin (NCBI)

GO Terms: GO:0006118, GO:0006879, GO:0046914, GO:0008199, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1136

Tuberculist Genomic Region

MMP0097 Transcriptional regulator protein, Helix-turn-helix motif (NCBI)

Details for MMP0097 - Transcriptional regulator protein, Helix-turn-helix motif (NCBI)

GO Terms: GO:0043565

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0097

Tuberculist Genomic Region

MMP1229 conserved hypothetical protein (NCBI)

Details for MMP1229 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1229

Tuberculist Genomic Region

MMP0180 riboflavin synthase (NCBI)

Details for MMP0180 - riboflavin synthase (NCBI)

GO Terms: GO:0009231, GO:0009349, GO:0004746

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0180

Tuberculist Genomic Region

MMP1439 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 (NCBI)

Details for MMP1439 - 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 (NCBI)

GO Terms: GO:0046872, GO:0046538, GO:0046537

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1439

Tuberculist Genomic Region

MMP0210 Conserved hypothetical protein (NCBI)

Details for MMP0210 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0210

Tuberculist Genomic Region

MMP0059 conserved hypothetical archaeal protein (NCBI)

Details for MMP0059 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0059

Tuberculist Genomic Region

MMP0369 conserved hypothetical protein (NCBI)

Details for MMP0369 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0369

Tuberculist Genomic Region

MMP0096 Aminotransferase (subgroup I) (NCBI)

Details for MMP0096 - Aminotransferase (subgroup I) (NCBI)

GO Terms: GO:0009058, GO:0016769, GO:0030170

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0096

Tuberculist Genomic Region

MMP0480 conserved hypothetical protein (NCBI)

Details for MMP0480 - conserved hypothetical protein (NCBI)

GO Terms: GO:0006367, GO:0005673, GO:0003702

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0480

Tuberculist Genomic Region

MMP0181 hypothetical protein (NCBI)

Details for MMP0181 - hypothetical protein (NCBI)

GO Terms: GO:0005615

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0181

Tuberculist Genomic Region

MMP0487 Hypothetical protein (NCBI)

Details for MMP0487 - Hypothetical protein (NCBI)

GO Terms: GO:0016192, GO:0006935, GO:0007165, GO:0016020, GO:0004871, GO:0005515

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0487

Tuberculist Genomic Region

MMP0209 Conserved hypothetical protein (NCBI)

Details for MMP0209 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0043565

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0209

Tuberculist Genomic Region

MMP0613 Alpha-acetolactate decarboxylase (NCBI)

Details for MMP0613 - Alpha-acetolactate decarboxylase (NCBI)

GO Terms: GO:0047605

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0613

Tuberculist Genomic Region

MMP0256 Imidazoleglycerol-phosphate synthase, amidotransferase subunit (NCBI)

Details for MMP0256 - Imidazoleglycerol-phosphate synthase, amidotransferase subunit (NCBI)

GO Terms: GO:0000105, GO:0006541, GO:0005737, GO:0016763

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0256

Tuberculist Genomic Region

MMP0712 similar to amino acid ABC transporter substrate-binding protein (NCBI)

Details for MMP0712 - similar to amino acid ABC transporter substrate-binding protein (NCBI)

GO Terms: GO:0006810, GO:0030288, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0712

Tuberculist Genomic Region

MMP0257 TATA-binding protein (TBP) (NCBI)

Details for MMP0257 - TATA-binding protein (TBP) (NCBI)

GO Terms: GO:0006367, GO:0006355, GO:0005669, GO:0003677, GO:0003702

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0257

Tuberculist Genomic Region

MMP0722 Conserved Hypothetical Archael Protein (NCBI)

Details for MMP0722 - Conserved Hypothetical Archael Protein (NCBI)

GO Terms: GO:0006118, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0722

Tuberculist Genomic Region

MMP1493 conserved hypothetical protein (NCBI)

Details for MMP1493 - conserved hypothetical protein (NCBI)

GO Terms: GO:0005618

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1493

Tuberculist Genomic Region

MMP0757 conserved hypothetical protein (NCBI)

Details for MMP0757 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0757

Tuberculist Genomic Region

MMP1550 NADP oxidoreductase, coenzyme F420-dependent (NCBI)

Details for MMP1550 - NADP oxidoreductase, coenzyme F420-dependent (NCBI)

GO Terms: GO:0006118

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1550

Tuberculist Genomic Region

MMP0788 Conserved hypothetical protein (NCBI)

Details for MMP0788 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0016192, GO:0006935, GO:0007165, GO:0016020, GO:0004871, GO:0005515

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0788

Tuberculist Genomic Region

MMP0734 hypothetical protein (NCBI)

Details for MMP0734 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0734

Tuberculist Genomic Region

MMP0922 possible phage infection protein (NCBI)

Details for MMP0922 - possible phage infection protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0922

Tuberculist Genomic Region

MMP0932 probable chemotaxis-related protein (NCBI)

Details for MMP0932 - probable chemotaxis-related protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0932

Tuberculist Genomic Region

MMP0923 Dihydrodipicolinate reductase (NCBI)

Details for MMP0923 - Dihydrodipicolinate reductase (NCBI)

GO Terms: GO:0009089, GO:0005737, GO:0008839

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0923

Tuberculist Genomic Region

MMP0524 possible (U93872) ORF 73, contains large complex repeat CR 73 [Human herpesvirus 8] (NCBI)

Details for MMP0524 - possible (U93872) ORF 73, contains large complex repeat CR 73 [Human herpesvirus 8] (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0524

Tuberculist Genomic Region

MMP1134 type A flavoprotein (NCBI)

Details for MMP1134 - type A flavoprotein (NCBI)

GO Terms: GO:0010181, GO:0016491, GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1134

Tuberculist Genomic Region

Displaying 1 - 31 of 31

Motifs

Motif 1: e-value: 0.39 e-value: 1200

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0907

predicted archaeal transcriptional regulator (NCBI)
 down-regulates -0.42

MMP0907

MMP1015

Transcription factor CBF/NF-Y/archaeal histone:Histone-fold/TFIID-TAF/NF-Y domain (NCBI)
 up-regulates 0.29

MMP1015

MMP0168

Transcriptional regulator PadR-like family (NCBI)
 up-regulates 0.29

MMP0168

GO Enrichment

Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016866 intramolecular transferase activity 4 0.06 2 0.0013
MF GO:0050662 coenzyme binding 28 0.43 3 0.0075
MF GO:0010181 FMN binding 10 0.16 2 0.0093
MF GO:0048037 cofactor binding 32 0.50 3 0.0110
MF GO:0043565 sequence-specific DNA binding 11 0.17 2 0.0113
MF GO:0016853 isomerase activity 14 0.22 2 0.0181
MF GO:0016628 oxidoreductase activity, acting on the C... 3 0.05 1 0.0459
MF GO:0003677 DNA binding 56 0.87 3 0.0496

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