Methanococcus maripaludis S2 Module 63 Residual: 0.16

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Summary

Residual: 0.16 Score: -23.9453 version: mmp_cmonkey_11_Oct_11

Members

MMP0952 translation initiation factor IF-5a (NCBI)

Details for MMP0952 - translation initiation factor IF-5a (NCBI)

GO Terms: GO:0006413, GO:0003743

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0952

Tuberculist Genomic Region

MMP1658 SSU ribosomal protein S8E (NCBI)

Details for MMP1658 - SSU ribosomal protein S8E (NCBI)

GO Terms: GO:0005622

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1658

Tuberculist Genomic Region

MMP1360 RNA polymerase H/23 kD subunit (NCBI)

Details for MMP1360 - RNA polymerase H/23 kD subunit (NCBI)

GO Terms: GO:0006350, GO:0003902, GO:0003900, GO:0003677, GO:0003899, GO:0003901

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1360

Tuberculist Genomic Region

MMP1148 Small nuclear ribonucleoprotein (Sm protein) (NCBI)

Details for MMP1148 - Small nuclear ribonucleoprotein (Sm protein) (NCBI)

GO Terms: GO:0016071, GO:0030529

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1148

Tuberculist Genomic Region

MMP1362 Glycoside hydrolase, family 1:DNA-directed RNA polymerase, beta subunit:ATP/GTP-binding site motif A (P-loop) (NCBI)

Details for MMP1362 - Glycoside hydrolase, family 1:DNA-directed RNA polymerase, beta subunit:ATP/GTP-binding site motif A (P-loop) (NCBI)

GO Terms: GO:0006350, GO:0005975, GO:0003902, GO:0003900, GO:0003677, GO:0003899, GO:0004553, GO:0003901

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1362

Tuberculist Genomic Region

MMP0156 Ribosomal protein S19E (S16A) (NCBI)

Details for MMP0156 - Ribosomal protein S19E (S16A) (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0156

Tuberculist Genomic Region

MMP1371 SSU ribosomal protein S10 (NCBI)

Details for MMP1371 - SSU ribosomal protein S10 (NCBI)

GO Terms: GO:0006412, GO:0015935, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1371

Tuberculist Genomic Region

MMP1544 LSU Ribosomal protein L4P (NCBI)

Details for MMP1544 - LSU Ribosomal protein L4P (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1544

Tuberculist Genomic Region

MMP1406 Protein translation factor SUI1 homolog (NCBI)

Details for MMP1406 - Protein translation factor SUI1 homolog (NCBI)

GO Terms: GO:0006413, GO:0003743

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1406

Tuberculist Genomic Region

MMP1545 LSU Ribosomal protein L23P (NCBI)

Details for MMP1545 - LSU Ribosomal protein L23P (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735, GO:0003723, GO:0000166

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1545

Tuberculist Genomic Region

MMP1543 LSU Ribosomal protein L3P (NCBI)

Details for MMP1543 - LSU Ribosomal protein L3P (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1543

Tuberculist Genomic Region

Displaying 1 - 11 of 11

Motifs

Motif 1: e-value: 51 e-value: 130

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0460

Conserved Hypothetical Protein (NCBI)
 down-regulates -0.47

MMP0460

MMP0907

predicted archaeal transcriptional regulator (NCBI)

MMP1646

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.35

MMP0907

MMP1646

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP0257

TATA-binding protein (TBP) (NCBI)
 down-regulates -0.23

MMP0052

MMP0257

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)
 down-regulates -0.14

MMP0052

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0009889 regulation of biosynthetic process 5 0.03 1 0.0260
BP GO:0010468 regulation of gene expression 5 0.03 1 0.0260
BP GO:0010556 regulation of macromolecule biosynthetic... 5 0.03 1 0.0260
BP GO:0019222 regulation of metabolic process 5 0.03 1 0.0260
BP GO:0031323 regulation of cellular metabolic process 5 0.03 1 0.0260
BP GO:0031326 regulation of cellular biosynthetic proc... 5 0.03 1 0.0260
BP GO:0060255 regulation of macromolecule metabolic pr... 5 0.03 1 0.0260
BP GO:0080090 regulation of primary metabolic process 5 0.03 1 0.0260
BP GO:2000112 regulation of cellular macromolecule bio... 5 0.03 1 0.0260
BP GO:0010467 gene expression 7 0.04 1 0.0365
BP GO:0009059 macromolecule biosynthetic process 8 0.04 1 0.0417
BP GO:0034645 cellular macromolecule biosynthetic proc... 8 0.04 1 0.0417
Category: CC
Category GO ID GO Term Annotated Expected Significant p-value
CC GO:0030529 ribonucleoprotein complex 36 0.99 4 0.0058
CC GO:0044424 intracellular part 71 1.96 5 0.0085
CC GO:0032991 macromolecular complex 41 1.13 4 0.0097
CC GO:0005622 intracellular 76 2.10 5 0.0121
CC GO:0005623 cell 85 2.35 5 0.0214
CC GO:0044464 cell part 85 2.35 5 0.0214
CC GO:0005840 ribosome 32 0.88 3 0.0393
CC GO:0043226 organelle 32 0.88 3 0.0393
CC GO:0043228 non-membrane-bounded organelle 32 0.88 3 0.0393
CC GO:0043229 intracellular organelle 32 0.88 3 0.0393
CC GO:0043232 intracellular non-membrane-bounded organ... 32 0.88 3 0.0393
CC GO:0044444 cytoplasmic part 34 0.94 3 0.0466
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0003676 nucleic acid binding 122 0.79 4 0.0026
MF GO:0019843 rRNA binding 26 0.17 2 0.0102
MF GO:0097159 organic cyclic compound binding 329 2.13 5 0.0137
MF GO:1901363 heterocyclic compound binding 329 2.13 5 0.0137
MF GO:0003677 DNA binding 56 0.36 2 0.0447
MF GO:0003723 RNA binding 57 0.37 2 0.0463

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