MMP1362 MMP1362 Glycoside hydrolase, family 1:DNA-directed RNA polymerase, beta subunit:ATP/GTP-binding site motif A (P-loop) (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP1362 MMP1362 rpoB1 rpoB1, MMP1362 Glycoside hydrolase, family 1:DNA-directed RNA polymerase, beta subunit:ATP/GTP-binding site motif... DNA-directed RNA polymerase (EC 2.7.7.6) 1340896 1342731 + 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0063 0.16
mmp-bicluster_0130 0.23
mmp-bicluster_0140 0.37

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG
Q6LXI9 2762416 NP_988482.1; 45358925 533564 CAF30918 IPR015712, IPR007120, IPR007121, IPR007646, IPR007647, IPR007641, IPR014724, IPR019969 COG0085

Mutations

Line Position Effect Impact Class Percent Frequency Sample Title
HR2 1 341 204 CODON_INSERTION NONE 93 EP_HR2_01 BX950229-MMP1362-1341204-EP_HR2_01
HR2 1 341 204 CODON_INSERTION NONE 93 EP_HR2_05 BX950229-MMP1362-1341204-EP_HR2_05
HA2 1 341 830 NON_SYNONYMOUS_CODING MISSENSE 99 HA2.152.08.M01 BX950229-MMP1362-1341830-HA2.152.08.M01
HA2 1 341 830 NON_SYNONYMOUS_CODING MISSENSE 100 HA2.152.01.M01 BX950229-MMP1362-1341830-HA2.152.01.M01
HR2 1 341 204 CODON_INSERTION NONE 87 HR2.152.01.M02 BX950229-MMP1362-1341204-HR2.152.01.M02
HR2 1 341 204 CODON_INSERTION NONE 83 HR2.152.05.M01 BX950229-MMP1362-1341204-HR2.152.05.M01
HA2 1 341 830 NON_SYNONYMOUS_CODING MISSENSE 100 HA2.152.01.M03 BX950229-MMP1362-1341830-HA2.152.01.M03
HA2 1 341 830 NON_SYNONYMOUS_CODING MISSENSE 98 HA2.152.01.M02 BX950229-MMP1362-1341830-HA2.152.01.M02
HR2 1 341 204 CODON_INSERTION NONE 76 HR2.152.01.M03 BX950229-MMP1362-1341204-HR2.152.01.M03
HA2 1 341 830 NON_SYNONYMOUS_CODING MISSENSE 99 HA2.152.05.M03 BX950229-MMP1362-1341830-HA2.152.05.M03

Transposon mutants

Title Insert TAG Module
MMP1362

Homology

Orthologues Paralogues

Functions

Catalytic Activity EC Description Protein families
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). {ECO:0000256|RuleBase:RU000431}. (2.7.7.6) DNA-directed RNA polymerase. RNA polymerase beta chain family

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
0 0 0 0 4 1 0 0 0 6

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45358925 NP_988482.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP1362

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