Methanococcus maripaludis S2 Module 125 Residual: 0.24 | Syntrophy Portal

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Summary

Residual: 0.24 Score: -24.1488 version: mmp_cmonkey_11_Oct_11

Members

MMP0292 hypothetical protein (NCBI) Details for MMP0292 - hypothetical protein (NCBI) GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0292 Tuberculist Genomic Region	MMP0434 conserved hypothetical protein (NCBI) Details for MMP0434 - conserved hypothetical protein (NCBI) GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0434 Tuberculist Genomic Region
MMP0293 conserved hypothetical protein (NCBI) Details for MMP0293 - conserved hypothetical protein (NCBI) GO Terms: GO:0008152, GO:0004332 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0293 Tuberculist Genomic Region	MMP0720 hydroxylamine reductase (RefSeq) Details for MMP0720 - hydroxylamine reductase (RefSeq) GO Terms: GO:0006118, GO:0005737, GO:0016661, GO:0051536 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0720 Tuberculist Genomic Region
MMP0614 related to iron-sulfur flavoprotein of Methanosarcina thermophila (NCBI) Details for MMP0614 - related to iron-sulfur flavoprotein of Methanosarcina thermophila (NCBI) GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0614 Tuberculist Genomic Region	MMP0996 hypothetical protein (NCBI) Details for MMP0996 - hypothetical protein (NCBI) GO Terms: GO:0009055 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0996 Tuberculist Genomic Region
MMP0721 ferredoxin (NCBI) Details for MMP0721 - ferredoxin (NCBI) GO Terms: GO:0006118, GO:0009055, GO:0051536 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0721 Tuberculist Genomic Region	MMP0997 Blue (type 1) copper domain (NCBI) Details for MMP0997 - Blue (type 1) copper domain (NCBI) GO Terms: GO:0006118, GO:0005507, GO:0009055 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0997 Tuberculist Genomic Region
MMP0852 conserved hypothetical protein (NCBI) Details for MMP0852 - conserved hypothetical protein (NCBI) GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0852 Tuberculist Genomic Region	MMP1165 Haloacid dehalogenase/epoxide hydrolase:ATPase, E1-E2 type:Heavy metal transport/detoxification protein (NCBI) Details for MMP1165 - Haloacid dehalogenase/epoxide hydrolase:ATPase, E1-E2 type:Heavy metal transport/detoxification protein (NCBI) GO Terms: GO:0006825, GO:0008152, GO:0016021, GO:0005524, GO:0046872, GO:0046873, GO:0004008 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP1165 Tuberculist Genomic Region
MMP1164 heavy-metal transport ATPase related protein (NCBI) Details for MMP1164 - heavy-metal transport ATPase related protein (NCBI) GO Terms: GO:0030001, GO:0046872 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP1164 Tuberculist Genomic Region	MMP1633 conserved hypothetical archaeal protein (NCBI) Details for MMP1633 - conserved hypothetical archaeal protein (NCBI) GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP1633 Tuberculist Genomic Region
MMP1174 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (NCBI) Details for MMP1174 - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (NCBI) GO Terms: GO:0051920 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP1174 Tuberculist Genomic Region	MMP1634 Protein of unknown function UPF0033:DsrE-like protein (NCBI) Details for MMP1634 - Protein of unknown function UPF0033:DsrE-like protein (NCBI) GO Terms: GO:0008033, GO:0005737, GO:0005515, GO:0016783 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP1634 Tuberculist Genomic Region
MMP0294 Bacterial quinoprotein (NCBI) Details for MMP0294 - Bacterial quinoprotein (NCBI) GO Terms: GO:0006118 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: MMP0294 Tuberculist Genomic Region

Motifs

Motif 1:

e-value: 0.0046 Motif 2:

e-value: 8.6

Module Median Expression Profiles

Module Plots

Regulation

Regulator	Interaction	Influence Weight	Other Influences
H2	down-regulates	-0.38	H2
MMP0086 LuxR family member (NCBI)	up-regulates	0.23	MMP0086
MMP0052 Conserved Hypothetical protein with 2 CBS domains (NCBI) MMP0993 conserved hypothetical helix-turn-helix protein (NCBI)	up-regulates	0.17	MMP0052 MMP0993
MMP1100 putative transricptional regulator (NCBI)	up-regulates	0.16	MMP1100

GO Enrichment

Category: BP
Category	GO ID	GO Term	Annotated	Expected	Significant	p-value
BP	GO:0045454	cell redox homeostasis	4	0.02	1	0.0210
BP	GO:0019725	cellular homeostasis	7	0.04	1	0.0360
BP	GO:0042592	homeostatic process	7	0.04	1	0.0360
BP	GO:0065008	regulation of biological quality	7	0.04	1	0.0360

Category: MF
Category	GO ID	GO Term	Annotated	Expected	Significant	p-value
MF	GO:0046872	metal ion binding	24	0.25	2	0.0230
MF	GO:0043169	cation binding	26	0.27	2	0.0270

Essentiality

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