Methanococcus maripaludis S2 Module 41 Residual: 0.48

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Summary

Residual: 0.48 Score: -11.0647 version: mmp_cmonkey_11_Oct_11

Members

MMP0108 ABC-type Iron(III)-binding periplasmic protein precursor (NCBI)

Details for MMP0108 - ABC-type Iron(III)-binding periplasmic protein precursor (NCBI)

GO Terms: GO:0006810, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0108

Tuberculist Genomic Region

MMP1585 Arginase (NCBI)

Details for MMP1585 - Arginase (NCBI)

GO Terms: GO:0006596, GO:0046872, GO:0008783

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1585

Tuberculist Genomic Region

MMP0141 conserved archaeal protein (NCBI)

Details for MMP0141 - conserved archaeal protein (NCBI)

GO Terms: GO:0006265, GO:0006268, GO:0005694, GO:0003916

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0141

Tuberculist Genomic Region

MMP1612 Conserved hypothetical protein (NCBI)

Details for MMP1612 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0006468, GO:0005524, GO:0004672

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1612

Tuberculist Genomic Region

MMP0216 cation transport ATPase (NCBI)

Details for MMP0216 - cation transport ATPase (NCBI)

GO Terms: GO:0008152, GO:0030001, GO:0016021, GO:0005261, GO:0015662, GO:0046872, GO:0005524, GO:0016463, GO:0008551

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0216

Tuberculist Genomic Region

MMP1651 periplasmic molybdate-binding protein (NCBI)

Details for MMP1651 - periplasmic molybdate-binding protein (NCBI)

GO Terms: GO:0015689, GO:0030288, GO:0015412

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1651

Tuberculist Genomic Region

MMP0493 cobaltochelatase (RefSeq)

Details for MMP0493 - cobaltochelatase (RefSeq)

GO Terms: GO:0009058, GO:0051116

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0493

Tuberculist Genomic Region

MMP0026 DNA-directed DNA polymerase II large subunit (NCBI)

Details for MMP0026 - DNA-directed DNA polymerase II large subunit (NCBI)

GO Terms: GO:0006308, GO:0006260, GO:0003677, GO:0003893, GO:0016449, GO:0019984, GO:0003889, GO:0003894, GO:0015999, GO:0016450, GO:0003890, GO:0003895, GO:0016000, GO:0016451, GO:0003891, GO:0016448, GO:0016452

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0026

Tuberculist Genomic Region

MMP0670 conserved hypothetical protein (NCBI)

Details for MMP0670 - conserved hypothetical protein (NCBI)

GO Terms: GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0670

Tuberculist Genomic Region

MMP0142 Thiamine pyrophosphate dependent enzyme related to acetolactate synthase (NCBI)

Details for MMP0142 - Thiamine pyrophosphate dependent enzyme related to acetolactate synthase (NCBI)

GO Terms: GO:0000287, GO:0003984, GO:0030976

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0142

Tuberculist Genomic Region

MMP0861 Lysine 2,3-aminomutase (NCBI)

Details for MMP0861 - Lysine 2,3-aminomutase (NCBI)

GO Terms: GO:0008152, GO:0050066, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0861

Tuberculist Genomic Region

MMP0144 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. (NCBI)

Details for MMP0144 - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. (NCBI)

GO Terms: GO:0008152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0144

Tuberculist Genomic Region

MMP0862 GCN5-related N-acetyltransferase (NCBI)

Details for MMP0862 - GCN5-related N-acetyltransferase (NCBI)

GO Terms: GO:0008152, GO:0008080

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0862

Tuberculist Genomic Region

MMP0610 PUA domain:Queuine/other tRNA-ribosyltransferase:Uncharacterized domain 2:Archaeosine tRNA-ribosyltransferase (NCBI)

Details for MMP0610 - PUA domain:Queuine/other tRNA-ribosyltransferase:Uncharacterized domain 2:Archaeosine tRNA-ribosyltransferase (NCBI)

GO Terms: GO:0008616, GO:0003723, GO:0008479

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0610

Tuberculist Genomic Region

MMP0866 putative glycine betaine/L-proline ABC transporter, solute-binding protein (NCBI)

Details for MMP0866 - putative glycine betaine/L-proline ABC transporter, solute-binding protein (NCBI)

GO Terms: GO:0006810, GO:0005215, GO:0005488

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0866

Tuberculist Genomic Region

MMP1150 Uroporphyrinogen decarboxylase (URO-D) (NCBI)

Details for MMP1150 - Uroporphyrinogen decarboxylase (URO-D) (NCBI)

GO Terms: GO:0006779, GO:0004853

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1150

Tuberculist Genomic Region

MMP0867 ABC-type proline/glycine betaine transport system, permease component related protein (NCBI)

Details for MMP0867 - ABC-type proline/glycine betaine transport system, permease component related protein (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0867

Tuberculist Genomic Region

MMP1200 Diaminopimelate decarboxylase (NCBI)

Details for MMP1200 - Diaminopimelate decarboxylase (NCBI)

GO Terms: GO:0009089, GO:0008836

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1200

Tuberculist Genomic Region

MMP0868 CBS domain:ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase (NCBI)

Details for MMP0868 - CBS domain:ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase (NCBI)

GO Terms: GO:0006865, GO:0016020, GO:0005524, GO:0015596, GO:0015171, GO:0016887, GO:0015418

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0868

Tuberculist Genomic Region

MMP1700 Na+/solute symporter (NCBI)

Details for MMP1700 - Na+/solute symporter (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1700

Tuberculist Genomic Region

MMP1334 Solute-binding protein/glutamate receptor:ATP/GTP-binding site motif A (P-loop):GTP-binding protein, HSR1-related:GTP-binding... (NCBI)

Details for MMP1334 - Solute-binding protein/glutamate receptor:ATP/GTP-binding site motif A (P-loop):GTP-binding protein, HSR1-related:GTP-binding... (NCBI)

GO Terms: GO:0015684, GO:0005622, GO:0016021, GO:0009276, GO:0005525, GO:0003924, GO:0015093

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1334

Tuberculist Genomic Region

MMP0146 conserved hypothetical protein (NCBI)

Details for MMP0146 - conserved hypothetical protein (NCBI)

GO Terms: GO:0006118, GO:0009228, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0146

Tuberculist Genomic Region

MMP1441 ATP/GTP-binding site motif A (P-loop):Molybdopterin-guanine dinucleotide biosynthesis protein (NCBI)

Details for MMP1441 - ATP/GTP-binding site motif A (P-loop):Molybdopterin-guanine dinucleotide biosynthesis protein (NCBI)

GO Terms: GO:0006777, GO:0051536, GO:0005525

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1441

Tuberculist Genomic Region

Displaying 1 - 23 of 23

Motifs

Motif 1: e-value: 160 e-value: 100

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP1303

Sensory transduction histidine kinase (NCBI)

H2

 up-regulates 0.42

MMP1303

H2

MMP0480

conserved hypothetical protein (NCBI)
 down-regulates -0.25

MMP0480

MMP0036

Transcription factor E (NCBI)

MMP0217

Transcriptional repressor related protein (NCBI)
 up-regulates 0.11

MMP0036

MMP0217

MMP0036

Transcription factor E (NCBI)

MMP1023

Transcriptional regulator, TetR Family Member (NCBI)
 up-regulates 0.11

MMP0036

MMP1023

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006778 porphyrin-containing compound metabolic ... 4 0.04 1 0.0410
BP GO:0006779 porphyrin-containing compound biosynthet... 4 0.04 1 0.0410
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016831 carboxy-lyase activity 5 0.10 2 0.0039
MF GO:0016820 hydrolase activity, acting on acid anhyd... 6 0.12 2 0.0057
MF GO:0016887 ATPase activity 6 0.12 2 0.0057
MF GO:0042623 ATPase activity, coupled 6 0.12 2 0.0057
MF GO:0042625 ATPase activity, coupled to transmembran... 6 0.12 2 0.0057
MF GO:0042626 ATPase activity, coupled to transmembran... 6 0.12 2 0.0057
MF GO:0043492 ATPase activity, coupled to movement of ... 6 0.12 2 0.0057
MF GO:0015399 primary active transmembrane transporter... 7 0.14 2 0.0079
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane... 7 0.14 2 0.0079
MF GO:0017111 nucleoside-triphosphatase activity 8 0.17 2 0.0105
MF GO:0016462 pyrophosphatase activity 9 0.19 2 0.0133
MF GO:0016817 hydrolase activity, acting on acid anhyd... 9 0.19 2 0.0133
MF GO:0016818 hydrolase activity, acting on acid anhyd... 9 0.19 2 0.0133
MF GO:0016830 carbon-carbon lyase activity 10 0.21 2 0.0164
MF GO:0005215 transporter activity 32 0.66 3 0.0250
MF GO:0022804 active transmembrane transporter activit... 14 0.29 2 0.0316
MF GO:0016787 hydrolase activity 62 1.28 4 0.0328

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