Methanococcus maripaludis S2 Module 117 Residual: 0.42

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Summary

Residual: 0.42 Score: -17.6256 version: mmp_cmonkey_11_Oct_11

Members

MMP0225 glycerol dehydrogenase (NCBI)

Details for MMP0225 - glycerol dehydrogenase (NCBI)

GO Terms: GO:0008152, GO:0009073, GO:0003856, GO:0046872, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0225

Tuberculist Genomic Region

MMP1330 Hydrogenase expression/formation protein (HUPF/HYPC) (NCBI)

Details for MMP1330 - Hydrogenase expression/formation protein (HUPF/HYPC) (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1330

Tuberculist Genomic Region

MMP0439 Dihydroorotate oxidase (NCBI)

Details for MMP0439 - Dihydroorotate oxidase (NCBI)

GO Terms: GO:0006222, GO:0006207, GO:0005737, GO:0004152, GO:0004158

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0439

Tuberculist Genomic Region

MMP1447 Cro repressor family Helix-turn-helix motif containing protein (NCBI)

Details for MMP1447 - Cro repressor family Helix-turn-helix motif containing protein (NCBI)

GO Terms: GO:0043565

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1447

Tuberculist Genomic Region

MMP1461 energy conserving hydrogenase A small subunit (NCBI)

Details for MMP1461 - energy conserving hydrogenase A small subunit (NCBI)

GO Terms: GO:0006120, GO:0008137, GO:0051539

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1461

Tuberculist Genomic Region

MMP1452 conserved hypothetical protein (NCBI)

Details for MMP1452 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1452

Tuberculist Genomic Region

MMP1619 Molybdenum cofactor biosynthesis protein:MoeA N-terminal region, domain I and II:MoeA C-terminal, domain IV (NCBI)

Details for MMP1619 - Molybdenum cofactor biosynthesis protein:MoeA N-terminal region, domain I and II:MoeA C-terminal, domain IV (NCBI)

GO Terms: GO:0006777

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1619

Tuberculist Genomic Region

MMP1453 conserved hypothetical protein (NCBI)

Details for MMP1453 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1453

Tuberculist Genomic Region

MMP1679 conserved hypothetical archeal protein (NCBI)

Details for MMP1679 - conserved hypothetical archeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1679

Tuberculist Genomic Region

MMP1662 Precorrin-4 C11-methyltransferase (NCBI)

Details for MMP1662 - Precorrin-4 C11-methyltransferase (NCBI)

GO Terms: GO:0009236, GO:0046026

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1662

Tuberculist Genomic Region

MMP0030 DNA replication protein; MCM family; putative (NCBI)

Details for MMP0030 - DNA replication protein; MCM family; putative (NCBI)

GO Terms: GO:0006270, GO:0003677, GO:0005524, GO:0008094

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0030

Tuberculist Genomic Region

MMP1665 hypothetical protein (NCBI)

Details for MMP1665 - hypothetical protein (NCBI)

GO Terms: GO:0006886, GO:0016192, GO:0006461, GO:0030117, GO:0008565, GO:0005515, GO:0005488

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1665

Tuberculist Genomic Region

MMP0052 Conserved Hypothetical protein with 2 CBS domains (NCBI)

Details for MMP0052 - Conserved Hypothetical protein with 2 CBS domains (NCBI)

GO Terms: GO:0008152, GO:0006821, GO:0016020, GO:0005247, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0052

Tuberculist Genomic Region

MMP0177 conserved hypothetical archaeal protein (NCBI)

Details for MMP0177 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0177

Tuberculist Genomic Region

MMP0226 conserved hypothetical protein (NCBI)

Details for MMP0226 - conserved hypothetical protein (NCBI)

GO Terms: GO:0006526, GO:0004055, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0226

Tuberculist Genomic Region

MMP1454 conserved hypothetical protein (NCBI)

Details for MMP1454 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1454

Tuberculist Genomic Region

MMP0289 Hydrogenase expression/formation protein (NCBI)

Details for MMP0289 - Hydrogenase expression/formation protein (NCBI)

GO Terms: GO:0046872

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0289

Tuberculist Genomic Region

MMP1456 conserved hypothetical protein (NCBI)

Details for MMP1456 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1456

Tuberculist Genomic Region

MMP0788 Conserved hypothetical protein (NCBI)

Details for MMP0788 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0016192, GO:0006935, GO:0007165, GO:0016020, GO:0004871, GO:0005515

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0788

Tuberculist Genomic Region

MMP1459 conserved hypothetical protein (NCBI)

Details for MMP1459 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1459

Tuberculist Genomic Region

MMP0849 L-lysine/ homoserine-homoserine lactone exporter family (NCBI)

Details for MMP0849 - L-lysine/ homoserine-homoserine lactone exporter family (NCBI)

GO Terms: GO:0006865, GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0849

Tuberculist Genomic Region

MMP1241 conserved hypothetical protein (NCBI)

Details for MMP1241 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1241

Tuberculist Genomic Region

MMP0992 conserved hypothetical archaeal protein (NCBI)

Details for MMP0992 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0992

Tuberculist Genomic Region

MMP1235 Molybdopterin biosynthesis MoaE (NCBI)

Details for MMP1235 - Molybdopterin biosynthesis MoaE (NCBI)

GO Terms: GO:0006777

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1235

Tuberculist Genomic Region

MMP1088 Glycosyl transferase, group 1 (NCBI)

Details for MMP1088 - Glycosyl transferase, group 1 (NCBI)

GO Terms: GO:0009058

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1088

Tuberculist Genomic Region

MMP1236 conserved hypothetical protein (NCBI)

Details for MMP1236 - conserved hypothetical protein (NCBI)

GO Terms: GO:0009228

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1236

Tuberculist Genomic Region

MMP1118 conserved hypothetical protein (NCBI)

Details for MMP1118 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1118

Tuberculist Genomic Region

Displaying 1 - 27 of 27

Motifs

Motif 1: e-value: 21 e-value: 34

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP1065

conserved hypothetical archaeal protein (NCBI)

MMP1210

 up-regulates 0.24

MMP1065

MMP1210

MMP1065

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.24

MMP1065

MMP0568

transcriptional regulator related protein (NCBI)
 down-regulates -0.23

MMP0568

MMP0527

conserved hypothetical archaeal protein (NCBI)

MMP1210

 up-regulates 0.17

MMP0527

MMP1210

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006810 transport 6 0.22 2 0.0160
BP GO:0051234 establishment of localization 6 0.22 2 0.0160
BP GO:0006777 Mo-molybdopterin cofactor biosynthetic p... 7 0.26 2 0.0220
BP GO:0019720 Mo-molybdopterin cofactor metabolic proc... 7 0.26 2 0.0220
BP GO:0032324 molybdopterin cofactor biosynthetic proc... 7 0.26 2 0.0220
BP GO:0043545 molybdopterin cofactor metabolic process 7 0.26 2 0.0220
BP GO:0051189 prosthetic group metabolic process 7 0.26 2 0.0220
BP GO:0051179 localization 8 0.29 2 0.0288
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0003954 NADH dehydrogenase activity 3 0.02 1 0.0230
MF GO:0008137 NADH dehydrogenase (ubiquinone) activity 3 0.02 1 0.0230
MF GO:0016655 oxidoreductase activity, acting on NAD(P... 3 0.02 1 0.0230
MF GO:0050136 NADH dehydrogenase (quinone) activity 3 0.02 1 0.0230
MF GO:0016651 oxidoreductase activity, acting on NAD(P... 4 0.03 1 0.0310

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