Organism : Clostridium acetobutylicum | Module List :
Possible hook-associated protein, flagellin family (NCBI ptt file)
Functional Annotations (4)
|Flagellin and related hook-associated proteins||cog/ cog|
|ciliary or flagellar motility||go/ biological_process|
|structural molecule activity||go/ molecular_function|
|bacterial-type flagellum filament||go/ cellular_component|
Regulation information for CAC2203(Mouseover regulator name to see its description)
Motif information (de novo identified motifs for modules)
There are 4 motifs predicted.
|Motif Id||e-value||Consensus||Motif Logo|
Functional Enrichment for CAC2203
Module neighborhood information for CAC2203
|Gene||Common Name||Description||Module membership|
|CAC0246||CAC0246||Conserved membrane protein, predicted permease (NCBI ptt file)||66, 113|
|CAC0247||CAC0247||Predicted permease (NCBI ptt file)||66, 356|
|CAC0304||motA||Chemotaxis motility protein A, gene motA (NCBI ptt file)||93, 96|
|CAC0305||motB||Chemotaxis motility protein B, gene motB (NCBI ptt file)||93, 96|
|CAC0450||CAC0450||Response regulator (CheY-like and HTH domains) (NCBI ptt file)||13, 66|
|CAC0522||CAC0522||Predicted hydrolase of the HAD superfamily (NCBI ptt file)||66, 282|
|CAC0559||CAC0559||Transcriptional regulator, MarR/EmrR family (NCBI ptt file)||66, 214|
|CAC0585||CAC0585||N-terminal CheY reciever domain fused to C-terminal uncharacterized CheX-like domain (NCBI ptt file)||66, 151|
|CAC0761||CAC0761||Predicted membrane protein (NCBI ptt file)||66, 86|
|CAC0778||CAC0778||ATP-dependent RNA helicase, superfamily II (NCBI ptt file)||13, 66|
|CAC0820||CAC0820||Conserved protein, ortholog YwqG B.subtilis (NCBI ptt file)||13, 66|
|CAC1233||chev||Chemotaxis protein CheV ortholog (CheW-like adaptor domain and CheY-like reciever domain) (NCBI ptt file)||93, 285|
|CAC1415||CAC1415||TerC family protein, ortholog of stress responce protein (NCBI ptt file)||34, 93|
|CAC1428||CAC1428||Hypothetical protein (NCBI ptt file)||93, 179|
|CAC1470||CAC1470||2-Hydroxy-6-Oxo-6-Phenylhexa-2,4-Dienoate hydrolase (NCBI ptt file)||66, 227|
|CAC1471||arbA||Ketopantoate reductase (NCBI ptt file)||66, 227|
|CAC1590||CAC1590||2-oxoglutarate/malate translocator (NCBI ptt file)||66, 249|
|CAC1600||CAC1600||Methyl-accepting chemotaxis-like protein (chemotaxis sensory transducer) (NCBI ptt file)||93, 299|
|CAC1634||CAC1634||Flagellin (NCBI ptt file)||93, 355|
|CAC2184||CAC2184||Uncharacterized protein, homolog HI1244 from Haemophilus influenzae (NCBI ptt file)||93, 122|
|CAC2185||CAC2185||Uncharacterized protein, homolog HI1244 from Haemophilus influenzae (NCBI ptt file)||52, 93|
|CAC2203||hag||Possible hook-associated protein, flagellin family (NCBI ptt file)||66, 93|
|CAC2325||CAC2325||Possible cell wall hydrolase containing N-acetylglucosaminidase domain and ChW-repeats (NCBI ptt file)||93, 122|
|CAC2617||CAC2617||Membrane associated methyl-chemotaxis protein, HAMP domain containing (NCBI ptt file)||66, 360|
|CAC2620||CAC2620||HD-GYP hydrolase domain containing protein (NCBI ptt file)||93, 299|
|CAC2773||CAC2773||Transcriptional regulators, AcrR family (NCBI ptt file)||93, 319|
|CAC2902||CAC2902||Isopentenyl monophosphate kinase, IPK (NCBI ptt file)||66, 247|
|CAC3047||CAC3047||Uncharacterized membrane protein, putative virulence factor MviN (NCBI ptt file)||93, 156|
|CAC3334||CAC3334||Multimeric flavodoxin WrbA family protein (NCBI ptt file)||66, 142|
|CAC3349||CAC3349||Transcriptional regulator, LysR family (NCBI ptt file)||66, 140|
|CAC3526||CAC3526||FMN-binding protein (NCBI ptt file)||66, 183|
|CAC3527||CAC3527||Ferredoxin (NCBI ptt file)||66, 249|
|CAC3556||CAC3556||Probable S-layer protein (NCBI ptt file)||31, 93|
|CAC3567||topB||Topoisomerase B (NCBI ptt file)||66, 270|
|CAC3686||CAC3686||Metallo-beta-lactamase superfamily hydrolase (NCBI ptt file)||33, 66|
Gene Page Help
If the gene is associated with a module(s), its connection to given modules along with other members of that module are shown as network by using CytoscapeWeb. In this view, each green colored circular nodes represent module member genes, purple colored diamonds represent module motifs and red triangles represent regulators. Each node is connected to module (Bicluster) via edges. This representation provides quick overview of all genes, regulators and motifs for modules. It also allows one to see shared genes/motifs/regulators among diferent modules.
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Network inference algorithm uses de novo motif prediction for assigning genes to modules. If there are any motifs identified in the upstream region of a gene, the motif will be shown here. For each motif sequence logo, consensus and e-value will be shown.
Identification of functional enrichment for the module members is important in associating predicted motifs and regulatory influences with pathways. As described above, the network inference pipeline includes a functional enrichment module by which hypergeometric p-values are used to identify over representation of functional ontology terms among module members.
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Module Members Tab
Identity of gene members in a module may help to identify potential interactions between different functional modules. Therefore, neighbor genes that share the same module(s) with gene under consideration are shown here. For each memebr, gene name, description and modules that contain it are listed.
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