Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 391 - 400 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_240	21 CD630_18700 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf29 \| Pathway: \| COG: Function unknown CD630_18690 - Type: Gene Product:Putative endonuclease relaxase Tn1549-like,CTn5-Orf28 \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_18711 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf31 \| Pathway: \| COG: CD630_18710 - Type: Gene Product:Putative oxidoreductase Tn1549-like, CTn5-Orf30 \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_32140 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_20010 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_11210 - pflC Type: Gene Product:Pyruvate formate-lyase 2-activating enzyme \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_04330 - Type: Gene Product:ABC-type transport system, multidrug-familypermease Tn1549-like, CTn2-Orf28 \| Pathway: \| COG: Defense mechanisms CD630_01450 - Type: Gene Product:Putative resolvase, S1 RNA-bindingdomain-containing protein \| Pathway: \| COG: Transcription CD630_18770 - vncS Type: Gene Product:Two-component sensor histidine kinase;Tn1549-like, CTn5-Orf37 \| Pathway: \| COG: Signal transduction mechanisms CD630_18740 - vexP2 Type: Gene Product:ABC-type transport system, ATP-binding proteinTn1549-like, CTn5-Orf34 \| Pathway: \| COG: Defense mechanisms CD630_11220 - Type: Gene Product:Transcriptional regulator, RmlC-type \| Pathway: \| COG: Transcription CD630_11200 - pflD Type: Gene Product:Formate acetyltransferase (Pyruvateformate-lyase) \| Pathway: \| COG: Energy production and conversion CD630_18760 - vncR Type: Gene Product:Two-component response regulator; Tn1549-like,CTn5-Orf36 \| Pathway: \| COG: Signal transduction mechanisms CD630_01460 - Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Secondary metabolites biosynthesis, transport and catabolism CD630_04270 - Type: Gene Product:Transcriptional regulator, HTH-type Tn1549-like,CTn2-Orf22 \| Pathway: \| COG: Transcription CD630_18720 - Type: Gene Product:Putative iron-sulfur binding protein Tn1549-like,CTn5-Orf32 \| Pathway: \| COG: Energy production and conversion CD630_18730 - vexP1 Type: Gene Product:ABC-type transport system, permease Tn1549-like,CTn5-Orf33 \| Pathway: \| COG: Defense mechanisms CD630_04280 - Type: Gene Product:Transcriptional regulator, AraC familyTn1549-like, CTn2-Orf23 \| Pathway: \| COG: Transcription CD630_20020 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_18750 - vexP3 Type: Gene Product:ABC-type transport system, permease Tn1549-like,CTn5-Orf35 \| Pathway: \| COG: Defense mechanisms	0.01	0.82	0.64	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_18860 - Type: Gene Product:Transcriptional regulator, PadR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_214	23 CD630_t0570 - tRNA-Ser Type: Gene Product: \| Pathway: \| COG: CD630_t0210 - tRNA-Lys Type: Gene Product: \| Pathway: \| COG: CD630_t0600 - tRNA-Trp Type: Gene Product: \| Pathway: \| COG: CD630_t0450 - tRNA-Val Type: Gene Product: \| Pathway: \| COG: CD630_03900 - bglG Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_11300 - Type: Gene Product:Putative lytic transglycosylase-like protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_t0720 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0700 - tRNA-Asn Type: Gene Product: \| Pathway: \| COG: CD630_02921 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_03880 - bglF Type: Gene Product:PTS system, beta-glucoside-specific IIABCcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_08140 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_t0440 - tRNA-Arg Type: Gene Product: \| Pathway: \| COG: CD630_33872 - Type: Gene Product:Fragment of conjugative transposon proteinTn916-like, CTn7-Orf26 (C-terminal region) \| Pathway: \| COG: CD630_t0220 - tRNA-Cys Type: Gene Product: \| Pathway: \| COG: CD630_t0750 - tRNA-Val Type: Gene Product: \| Pathway: \| COG: CD630_11310 - Type: Gene Product:Putative solute-binding lipoprotein \| Pathway: \| COG: Amino acid transport and metabolism CD630_t0560 - tRNA-Lys Type: Gene Product: \| Pathway: \| COG: CD630_22841 - Type: Gene Product:Fragment of putative beta-lactamase inducer(C-terminal region) \| Pathway: \| COG: CD630_08160 - bglF Type: Gene Product:PTS system, beta-glucoside-specific IIABCcomponent (Disrupted IStron) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_31382 - Type: Gene Product:Fragment of conserved hypothetical protein(Central region) \| Pathway: \| COG: CD630_03890 - bglA Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11280 - polA Type: Gene Product:DNA polymerase I (POLI) \| Pathway: \| COG: Replication, recombination and repair CD630_08150 - Type: Gene Product:Transporter, Major Facilitator Superfamily (MFS) \| Pathway: \| COG: Carbohydrate transport and metabolism	0	6.2e-32	0.65	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_25080 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_383	9 CD630_32690 - Type: Gene Product:Putative oligoendopeptidase F, M3B family \| Pathway: \| COG: Amino acid transport and metabolism CD630_31560 - Type: Gene Product:phage integrase \| Pathway: \| COG: Replication, recombination and repair CD630_19902 - cspC Type: Gene Product:Major cold shock protein CspC \| Pathway: \| COG: Transcription CD630_13950 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_32700 - Type: Gene Product:Putative magnesium transport ATPase, MgtC/SapBfamily \| Pathway: \| COG: Function unknown CD630_18080 - Type: Gene Product:Pyridoxal-dependent decarboxylase, group IVdecarboxylase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_23100 - cspD Type: Gene Product:Cold shock protein D \| Pathway: \| COG: Transcription CD630_18070 - Type: Gene Product:Putative NADPH-dependent FMN reductase \| Pathway: \| COG: Function unknown CD630_12341 - Type: Gene Product:Putative phage protein \| Pathway: \| COG:	`NA`	`NA`	0.65	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_05590 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_19100 - eutV Type: Gene Product:Two-component response regulator, Ethanolaminespecific \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_337	26 CD630_13781 - Type: Gene Product:Transcriptional regulator, Phage-type \| Pathway: \| COG: Function unknown CD630_35860 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_13782 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_08850 - glgP Type: Gene Product:Glycogen phosphorylase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_21460 - Type: Gene Product:Conserved hypothetical protein, UPF0027 family \| Pathway: \| COG: Replication, recombination and repair CD630_32890 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_32870 - Type: Gene Product:Putative oxidoreductase, FAD dependent \| Pathway: \| COG: Function unknown CD630_08120 - Type: Gene Product:Putative universal stress protein A (UspA) \| Pathway: \| COG: Signal transduction mechanisms CD630_22550 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_09040 - Type: Gene Product:Putative phage integrase \| Pathway: \| COG: Replication, recombination and repair CD630_22890 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_08840 - glgA Type: Gene Product:Glycogen synthase (Starch [bacterial glycogen]synthase) \| Pathway: Glycan biosynthesis \| COG: Carbohydrate transport and metabolism CD630_08820 - glgC Type: Gene Product:Glucose-1-phosphate adenylyltransferase \| Pathway: Glycan biosynthesis \| COG: Carbohydrate transport and metabolism CD630_07020 - Type: Gene Product:Putative membrane protein, DUF1275 family \| Pathway: \| COG: Function unknown CD630_08860 - Type: Gene Product:Putative alpha-amylase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_35870 - Type: Gene Product:Two-component response regulator, CheY family \| Pathway: \| COG: Signal transduction mechanisms CD630_35850 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_22880 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_32880 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_32860 - Type: Gene Product:Putative sodium:phosphate symporter \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_32900 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_32840 - HtrA Type: Gene Product:High temperature requirement A protease \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_08130 - Type: Gene Product:Putative PTS system, IIB component \| Pathway: \| COG: CD630_15790 - Type: Gene Product:Two-component sensor histidine kinase,sporulation-associated spo0A \| Pathway: \| COG: Signal transduction mechanisms CD630_35840 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_08830 - glgD Type: Gene Product:Glycogen biosynthesis protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis	0.000000000008	`NA`	0.65	Inferelator: 5 Hypergeometric: 1 TF Influences from Inferelator CD630_06700 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_20480 - Type: Gene Product:Transcriptional regulator, RpiR family \| Pathway: \| COG: Transcription CD630_22140 - SinR Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_35440 - Type: Gene Product:Transcriptional regulator, AsnC/Lrp family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test CD630_12750 - codY Type: Gene Product:Transcriptional regulator, GTP-sensingpleiotropic repressor \| Pathway: \| COG: Transcription
Module_207	8 CD630_06750 - Type: Gene Product:Putative acetyltransferase \| Pathway: \| COG: Function unknown CD630_08450 - Type: Gene Product:Putative nuclease \| Pathway: \| COG: Transcription CD630_13430 - glnA Type: Gene Product:Glutamine synthetase \| Pathway: \| COG: Amino acid transport and metabolism CD630_08460 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_21500 - Type: Gene Product:Putative endonuclease/exonuclease/phosphatase \| Pathway: \| COG: Function unknown CD630_24310 - Type: Gene Product:Putative nitrite/sulphite reductase \| Pathway: \| COG: Energy production and conversion CD630_35512 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06550 - Type: Gene Product:Putative beta-lactamase-like protein \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.65	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_28690 - Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_327	22 CD630_29470 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_29471 - Type: Gene Product:Hypothetical protein \| Pathway: \| COG: CD630_29430 - Type: Gene Product:Putative phage replication protein \| Pathway: \| COG: Replication, recombination and repair CD630_20120 - hydD Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Function unknown CD630_29450 - Type: Gene Product:Putative bacteriophage resistance protein \| Pathway: \| COG: Function unknown CD630_07810 - Type: Gene Product:Putative penicillin-binding protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_29510 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_14350 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_29490 - Type: Gene Product:Transcriptional regulator, Phage-type \| Pathway: \| COG: Transcription CD630_29460 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_20130 - hydR Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_29500 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_29440 - Type: Gene Product:Putative phage essential recombination functionprotein \| Pathway: \| COG: Replication, recombination and repair CD630_29520 - Type: Gene Product:Putative phage site-specific integrase \| Pathway: \| COG: Replication, recombination and repair CD630_29420 - Type: Gene Product:Putative phage resolvase/integrase \| Pathway: \| COG: CD630_14360 - Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Defense mechanisms CD630_01540 - hpdC Type: Gene Product:4-hydroxyphenylacetate decarboxylase, regulatorysubunit \| Pathway: \| COG: Function unknown CD630_14340 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_29480 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Transcription CD630_07820 - Type: Gene Product:Putative sporulation protein YunB \| Pathway: \| COG: Function unknown	0.000023	`NA`	0.65	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_11770 - fapR Type: Gene Product:Transcriptional regulator, DeoR family (Fattyacid and phospholipid biosynthesis regulator) \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_114	25 CD630_19010 - Type: Gene Product:Transcriptional regulator, Phage-type \| Pathway: \| COG: Function unknown CD630_21600 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Defense mechanisms CD630_29650 - Type: Gene Product:Putative signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_17070 - Type: Gene Product:Putative C4-dicarboxylate anaerobic carrier, DcuCfamily \| Pathway: \| COG: Function unknown CD630_09562 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_11260 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_06980 - Type: Gene Product:Putative tRNA/rRNA methyltransferase, SpoU \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_19810 - Type: Gene Product:Transcriptional regulator, hxlR family \| Pathway: \| COG: Transcription CD630_15740 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_14600 - Type: Gene Product:Putative phosphohydrolase, HD superfamily \| Pathway: \| COG: Function unknown CD630_16670 - Type: Gene Product:Putative maltose O-acetyltransferase \| Pathway: \| COG: Amino acid transport and metabolism CD630_06270 - Type: Gene Product:Putative transcriptional regulator, activatorMor \| Pathway: \| COG: CD630_06260 - Type: Gene Product:Putative replicative helicase DnaB-like \| Pathway: \| COG: Replication, recombination and repair CD630_20420 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_06090 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Nucleotide transport and metabolism CD630_14690 - cwp20 Type: Gene Product:Putative cell surface protein ; putativepenicillin-binding protein \| Pathway: \| COG: Defense mechanisms CD630_21590 - Type: Gene Product:Putative membrane protein, DUF1114 family \| Pathway: \| COG: Replication, recombination and repair CD630_28730 - Type: Gene Product:Putative signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_21650 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_19710 - Type: Gene Product:Putative protein, Sir2 family; putativesilencing, chromosome stability or ageing; putative ADPribosyltransferase \| Pathway: \| COG: Function unknown CD630_22440 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_18500 - Type: Gene Product:Transcriptional regulator, AraC family;Tn1549-like, CTn5-Orf6 \| Pathway: \| COG: Transcription CD630_18830 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_15150 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_19880 - Type: Gene Product:Putative tryptophan transport protein \| Pathway: \| COG: Function unknown	0.0000000089	`NA`	0.67	Inferelator: 3 Hypergeometric: 0 TF Influences from Inferelator CD630_16930 - Type: Gene Product:Putative dinitrogenase iron-molybdenum cofactor \| Pathway: \| COG: Function unknown CD630_19100 - eutV Type: Gene Product:Two-component response regulator, Ethanolaminespecific \| Pathway: \| COG: Signal transduction mechanisms CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_365	4 CD630_20470 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_34500 - Type: Gene Product:Putative oxidoreductase with NAD(P)-bindingRossmann-fold domain \| Pathway: \| COG: Function unknown CD630_13110 - Type: Gene Product:Putative phosphoesterase (Disrupted IStron) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis, Translation, ribosomal structure and biogenesis CD630_05850 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription	`NA`	`NA`	0.67	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_05790 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_132	12 CD630_29960 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_20260 - Type: Gene Product:Putative acetyltransferase \| Pathway: \| COG: Function unknown CD630_36210 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_20270 - Type: Gene Product:N-carbamoyl-L-amino acid hydrolase \| Pathway: \| COG: Amino acid transport and metabolism CD630_25410 - Type: Gene Product:Sodium:glutamate/aspartate symporter family \| Pathway: \| COG: Function unknown CD630_02791 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_36200 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_20280 - Type: Gene Product:Putative aspartate racemase RacX \| Pathway: \| COG: Amino acid transport and metabolism CD630_36690 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: Function unknown CD630_00210 - pycA Type: Gene Product:Pyruvate carboxylase \| Pathway: \| COG: Energy production and conversion CD630_16660 - Type: Gene Product:Putative membrane glycerophosphoryl diesterphosphodiesterase \| Pathway: \| COG: Energy production and conversion CD630_25170 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription	8.3	`NA`	0.69	Inferelator: 3 Hypergeometric: 0 TF Influences from Inferelator CD630_10090 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_20600 - Type: Gene Product:Putative lipid kinase \| Pathway: \| COG: Lipid transport and metabolism CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_71	24 CD630_36490 - rlmH Type: Gene Product:Ribosomal RNA large subunit methyltransferase H,SPOUT methyltransferase family \| Pathway: \| COG: Function unknown CD630_06900 - Type: Gene Product:Putative nucleotide phosphodiesterase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_19280 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11670 - recV Type: Gene Product:Tyrosine DNA recombinase, XerC/XerD family \| Pathway: \| COG: Replication, recombination and repair CD630_31580 - Type: Gene Product:Transcriptional regulator, TRAP family \| Pathway: \| COG: Function unknown CD630_04380 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_36530 - dnaD Type: Gene Product:DNA replication protein DnaD/DnaB \| Pathway: \| COG: Replication, recombination and repair CD630_36510 - Type: Gene Product:Putative metallo-beta-lactamase-like hydrolase \| Pathway: \| COG: Function unknown CD630_28820 - celF Type: Gene Product:Cellobiose-6-phosphate hydrolase, family 4 \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_14760 - Type: Gene Product:Putative signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_28800 - celC Type: Gene Product:PTS system, cellobiose-specific IIA component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_24680 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_28840 - celA Type: Gene Product:PTS system, cellobiose-specific IIB component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_24700 - gpr Type: Gene Product:Spore endopeptidase \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_36540 - dnaC Type: Gene Product:DNA replication protein DnaC \| Pathway: \| COG: Replication, recombination and repair CD630_36500 - Type: Gene Product:PTS system, lactose/cellobiose-family IICcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_28080 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_36520 - Type: Gene Product:Putative peptidase, M1 family \| Pathway: \| COG: Amino acid transport and metabolism CD630_28830 - celB Type: Gene Product:PTS system, cellobiose-specific IIC component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_24690 - spoIIP Type: Gene Product:Stage II sporulation protein P \| Pathway: \| COG: Function unknown CD630_07570 - Type: Gene Product:Phosphodiesterases protein \| Pathway: \| COG: Signal transduction mechanisms CD630_28810 - celG Type: Gene Product:Putative cellobiose-phosphate degrading protein \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_22010 - Type: Gene Product:Transporter, Major Facilitator Superfamily (MFS) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_24090 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	0.000000097	0	0.69	Inferelator: 1 Hypergeometric: 1 TF Influences from Inferelator CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test CD630_12140 - spo0A Type: Gene Product:Stage 0 sporulation protein A \| Pathway: \| COG: Signal transduction mechanisms