Top2a topoisomerase (DNA) II alpha (21973)

Symbol Product Feature Type Strand Chr
21973 Top2a topoisomerase (DNA) II alpha protein-coding 11
Synonyms
Top-2
GO ID Category Definition Evidence
  • nucleotide binding
  • nuclear chromosome
  • magnesium ion binding
  • resolution of meiotic recombination intermediates
  • condensed chromosome
  • synaptonemal complex
  • sister chromatid segregation
  • DNA binding
  • chromatin binding
  • DNA topoisomerase activity
  • DNA topoisomerase type II (ATP-hydrolyzing) activity
  • protein kinase C binding
  • ATP binding
  • nucleus
  • nucleoplasm
  • nucleolus
  • centriole
  • ATP catabolic process
  • DNA metabolic process
  • DNA-dependent DNA replication
  • DNA topological change
  • DNA ligation
  • mitotic recombination
  • cellular response to DNA damage stimulus
  • chromosome segregation
  • protein C-terminus binding
  • DNA-dependent ATPase activity
  • drug binding
  • DNA binding, bending
  • DNA topoisomerase complex (ATP-hydrolyzing)
  • isomerase activity
  • enzyme binding
  • chromosome condensation
  • apoptotic chromosome condensation
  • embryonic cleavage
  • protein homodimerization activity
  • histone deacetylase binding
  • positive regulation of apoptotic process
  • ubiquitin binding
  • protein complex
  • sequence-specific DNA binding
  • structure-specific DNA binding
  • mitotic DNA integrity checkpoint
  • positive regulation of viral genome replication
  • positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
  • positive regulation of transcription from RNA polymerase II promoter
  • metal ion binding
  • protein heterodimerization activity
Motif 1 Motif 2 Residual
PITA_155 |
Residual: 
0.24
0.24
PITA_175 |
Residual: 
0.26
0.26
PITA_20 |
Residual: 
0.20
0.20
TargetScan_127 |
Residual: 
0.19
0.19
TargetScan_72 |
Residual: 
0.14
0.14
Displaying 1 - 5 of 5
Entrez ID STRINGS Network
STRING
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