Organism : Rhodobacter sphaeroides 2.4.1 | Module List :
Regulation information for RSP_3495(Mouseover regulator name to see its description)
Motif information (de novo identified motifs for modules)
There are 4 motifs predicted.
|Motif Id||e-value||Consensus||Motif Logo|
Module neighborhood information for RSP_3495
|Gene||Common Name||Description||Module membership|
|RSP_0186||RSP_0186||Transcriptional regulator, TetR family (NCBI)||92, 370|
|RSP_0204||RSP_0204||metallo-beta-lactamase family protein (NCBI)||285, 370|
|RSP_0318||RSP_0318||hypothetical protein (NCBI)||116, 362|
|RSP_0319||RSP_0319||NnrU (NCBI)||116, 362|
|RSP_0320||NnrT||NnrT (NCBI)||116, 362|
|RSP_0321||norD||NorD Nitric oxide reductase activation protein (NCBI)||116, 362|
|RSP_0322||norQ||NorQ protein required for nitric oxide reductase activity (NCBI)||116, 362|
|RSP_0323||norB||Nitric oxide reductase large subunit, cytochrome b (NCBI)||116, 362|
|RSP_0324||norC||nitric oxide reductase subunit C, cytochrome c (NCBI)||116, 362|
|RSP_0325||RSP_0325||hypothetical protein (NCBI)||116, 362|
|RSP_0330||RSP_0330||hypothetical protein (NCBI)||74, 116|
|RSP_0605||RSP_0605||hypothetical protein (NCBI)||249, 370|
|RSP_0783||RSP_0783||hypothetical protein (NCBI)||116, 240|
|RSP_0790||pqqE||probable Coenzyme PQQ synthesis protein E (NCBI)||116, 338|
|RSP_0952||RSP_0952||Transglutaminase-like protein (NCBI)||249, 370|
|RSP_1323||RSP_1323||hypothetical protein (NCBI)||116, 304|
|RSP_1521||RSP_1521||hypothetical protein (NCBI)||97, 116|
|RSP_1611||RSP_1611||sensor histidine kinase (NCBI)||35, 370|
|RSP_1612||RSP_1612||Sigma-54 dependent transcriptional regulator (NCBI)||370, 379|
|RSP_2291||RSP_2291||hypothetical protein (NCBI)||14, 370|
|RSP_2429||RSP_2429||Glutathione-regulated potassium-efflux system protein, kefB (NCBI)||36, 370|
|RSP_2432||RSP_2432||hypothetical protein (NCBI)||31, 370|
|RSP_2433||cheY2||Chemotaxis response regulator, CheY2 (NCBI)||285, 370|
|RSP_2434||cheR1||Putative MCP methyltransferase, CheR1 (NCBI)||31, 370|
|RSP_2435||cheW1||Putative chemotaxis scaffold protein, CheW1 (NCBI)||31, 370|
|RSP_2436||cheA1||Chemotaxis histidine protein kinase, CheA1 (NCBI)||31, 370|
|RSP_2437||cheY1||chemotaxis response regulator, CheY1 (NCBI)||31, 370|
|RSP_2438||cheX||Putative CheX protein (NCBI)||31, 370|
|RSP_2439||cheD||putative chemotaxis protein, CheD (NCBI)||31, 370|
|RSP_2440||mcpA||Methyl accepting chemotaxis protein (NCBI)||31, 370|
|RSP_2721||RSP_2721||hypothetical protein (NCBI)||38, 370|
|RSP_2754||RSP_2754||hypothetical protein (NCBI)||105, 116|
|RSP_3018||RSP_3018||putative acyl-CoA dehydrogenase (NCBI)||304, 370|
|RSP_3060||cysE||possible O-acetylserine synthase (NCBI)||141, 370|
|RSP_3062||fabG||3-oxoacyl-(acyl-carrier-protein) reductase (NCBI)||141, 370|
|RSP_3116||RSP_3116||Conserved hypothetical membrane/transport protein (NCBI)||246, 370|
|RSP_3273||RSP_3273||ABC multidrug/carbohydrate efflux transporter, inner membrane subunit (NCBI)||116, 209|
|RSP_3274||RSP_3274||ABC multidrug/carbohydrate efflux transporter, ATPase subunit (NCBI)||116, 209|
|RSP_3275||RSP_3275||MoxR-like ATPase (NCBI)||82, 116|
|RSP_3276||RSP_3276||hypothetical protein (NCBI)||82, 116|
|RSP_3278||RSP_3278||Von Willebrand domain containing protein (NCBI)||62, 116|
|RSP_3280||RSP_3280||hypothetical protein (NCBI)||82, 116|
|RSP_3281||RSP_3281||hypothetical protein (NCBI)||82, 116|
|RSP_3282||RSP_3282||hypothetical protein (NCBI)||82, 116|
|RSP_3283||RSP_3283||myo-inositol 2-dehydrogenase (NCBI)||116, 304|
|RSP_3316||RSP_3316||hypothetical protein (NCBI)||82, 116|
|RSP_3428||RSP_3428||hypothetical protein (NCBI)||14, 116|
|RSP_3429||RSP_3429||hypothetical protein (NCBI)||11, 116|
|RSP_3451||RSP_3451||TRAP-T family transporter, large (12TMs) inner membrane subunit (NCBI)||61, 370|
|RSP_3493||RSP_3493||hypothetical protein (NCBI)||220, 370|
|RSP_3495||RSP_3495||hypothetical protein (NCBI)||116, 370|
|RSP_3496||RSP_3496||Zinc carboxypeptidase A metalloprotease (M14) (NCBI)||220, 370|
|RSP_3498||RSP_3498||Antifreeze protein, type I (NCBI)||103, 370|
|RSP_3684||solR||transcriptional regulator, LuxR family (NCBI)||116, 235|
|RSP_3830||RSP_3830||hypothetical protein (NCBI)||116, 220|
Gene Page Help
If the gene is associated with a module(s), its connection to given modules along with other members of that module are shown as network by using CytoscapeWeb. In this view, each green colored circular nodes represent module member genes, purple colored diamonds represent module motifs and red triangles represent regulators. Each node is connected to module (Bicluster) via edges. This representation provides quick overview of all genes, regulators and motifs for modules. It also allows one to see shared genes/motifs/regulators among diferent modules.
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Regulation tab for each gene includes regulatory influences such as environmental factors or transcription factors or their combinations identified by regulatory network inference algorithms.
If the gene is a member of a module, regulators influencing that module are also considered to regulate the gene. Regulators table list total number of regulatory influences, regulators, modules and type of the influence.
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Network inference algorithm uses de novo motif prediction for assigning genes to modules. If there are any motifs identified in the upstream region of a gene, the motif will be shown here. For each motif sequence logo, consensus and e-value will be shown.
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Identity of gene members in a module may help to identify potential interactions between different functional modules. Therefore, neighbor genes that share the same module(s) with gene under consideration are shown here. For each memebr, gene name, description and modules that contain it are listed.
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CircVisOur circular module explorer is adapted from visquick originally developed by Dick Kreisberg of Ilya Shmulevich lab at ISB for The Cancer Genome Atlas. We use simplified version of visquick to display distribution of module members and their interactions across the genome. This view provides summary of regulation information for a gene. The main components are;
- 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this example chromosome and pDV represent main chromosome and plasmid for D. vulgaris Hildenborough, respectively.
- 2. Source gene
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