MSMEG_0826 MSMEG_0826 Phosphomethylpyrimidine synthase (EC 4.1.99.17) (Hydroxymethylpyrimidine phosphate synthase) (Thiamine biosynthesis protein ThiC)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_0826	MSMEG_0826	thiC	thiC, MSMEG_0826		Phosphomethylpyrimidine synthase (EC 4.1.99.17) (Hydroxymethylpyrimidine phosphate synthase) (Thiamine biosynthesis protein ThiC)

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0093	0.56
msm_bicluster_0476	0.53

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0QQP2	4536005;	WP_011727222.1, YP_885230.1	ABK69726	IPR002817, IPR025747	COG0422, ENOG4105CBF	EOG6NWBM5

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
5-amino-1-(5-phospho-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + CO, ECO:0000256|HAMAP-Rule:MF_00089, ECO:0000256|SAAS:SAAS00390817}.	msm:MSMEG_0826	Cofactor biosynthesis, thiamine diphosphate biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00089, ECO:0000256|SAAS:SAAS00341091}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0051539 GO:0016829 GO:0009228 GO:0009229 GO:0008270 -

GO:0051539

GO:0016829

GO:0009228

GO:0009229

GO:0008270

String Network

Link to STRINGS	STRINGS Network
MSMEG_0826

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