MSMEG_1290 MSMEG_1290 Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_1290	MSMEG_1290	ilvD	ilvD, MSMEG_1290, MSMEI_1252		Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0076	0.50
msm_bicluster_0190	0.60

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0QRZ2	4535696;	WP_011727570.1, YP_885680.1	ABK74353, AFP37728, AIU06532	IPR015928, IPR004404, IPR000581, IPR020558	COG0129, ENOG4105C01	EOG6MSS24

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H(2)O, ECO:0000256|HAMAP-Rule:MF_00012, ECO:0000256|SAAS:SAAS00349165}.	msb:LJ00_06425, msg:MSMEI_1252, msm:MSMEG_1290	Amino-acid biosynthesis, L-isoleucine biosynthesis, L-isoleucine from 2-oxobutanoate: step 3/4. {ECO:0000256|HAMAP-Rule:MF_00012, ECO:0000256|SAAS:SAAS00349170}., Amino-acid biosynthesis, L-valine biosynthesis, L-valine from pyruvate: step 3/4. {ECO:0000256|HAMAP-Rule:MF_00012, ECO:0000256|SAAS:SAAS00349164}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0051539 GO:0004160 GO:0009097 GO:0046872 GO:0009099 -

GO:0051539

GO:0004160

GO:0009097

GO:0046872

GO:0009099

String Network

Link to STRINGS	STRINGS Network
MSMEG_1290

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