MSMEG_5224 MSMEG_5224 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_5224	MSMEG_5224	ispH	ispH, MSMEG_5224		4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2)

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0028	0.58
msm_bicluster_0453	0.48

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R2T2	4530979;	WP_011730396.1, YP_889470.1	ABK75503	IPR003451	COG0761, ENOG4105C48	EOG6HF624

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
Dimethylallyl diphosphate + NAD(P)(+) + H(2)O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H, ECO:0000256|HAMAP-Rule:MF_00191, ECO:0000256|SAAS:SAAS00389019}.; Isopentenyl diphosphate + NAD(P)(+) + H(2)O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H, ECO:0000256|HAMAP-Rule:MF_00191, ECO:0000256|SAAS:SAAS00389024}.	msm:MSMEG_5224	Isoprenoid biosynthesis, dimethylallyl diphosphate biosynthesis, dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. {ECO:0000256|HAMAP-Rule:MF_00191, ECO:0000256|SAAS:SAAS00389088}., Isoprenoid biosynthesis, isopentenyl diphosphate biosynthesis via DXP pathway, isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. {ECO:0000256|HAMAP-Rule:MF_00191, ECO:0000256|SAAS:SAAS00389010}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0051538 GO:0051745 GO:0050992 GO:0019288 GO:0046872 GO:0016114 -

GO:0051538

GO:0051745

GO:0050992

GO:0019288

GO:0046872

GO:0016114

String Network

Link to STRINGS	STRINGS Network
MSMEG_5224

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