MSMEG_6646 MSMEG_6646 2-methylisocitrate lyase (2-MIC) (MICL) (EC 4.1.3.30) ((2R,3S)-2-methylisocitrate lyase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_6646	MSMEG_6646	prpB	prpB, MSMEG_6646, MSMEI_6467		2-methylisocitrate lyase (2-MIC) (MICL) (EC 4.1.3.30) ((2R,3S)-2-methylisocitrate lyase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0061	0.53
msm_bicluster_0094	0.56

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R6R7	4533176;	WP_011731425.1, YP_890855.1	ABK71535, AFP42893, AIU11616	IPR018523, IPR012695, IPR015813	COG2513, ENOG4105CR4	EOG6BGP03

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate, ECO:0000256|HAMAP-Rule:MF_01939, ECO:0000256|RuleBase:RU361121}.	msb:LJ00_32845, msg:MSMEI_6467, msm:MSMEG_6646	Organic acid metabolism, propanoate degradation. {ECO:0000256|HAMAP-Rule:MF_01939, ECO:0000256|RuleBase:RU361121}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0000287 GO:0046421 GO:0019629 -

GO:0000287

GO:0046421

GO:0019629

String Network

Link to STRINGS	STRINGS Network
MSMEG_6646

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