MSMEG_2387 MSMEG_2387 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (Isopropylmalate isomerase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_2387	MSMEG_2387	leuC	leuC, MSMEG_2387, MSMEI_2327		3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) (Alpha-IPM isomerase) (Isopropylmalate isomerase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0153	0.42
msm_bicluster_0374	0.50

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0QUY9	4535787;	WP_011728310.1, YP_886727.1	ABK71381, AFP38795, AIU07570	IPR004430, IPR015931, IPR015937, IPR001030, IPR015932, IPR018136	COG0065, ENOG4105CQI	EOG600DP5

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate, ECO:0000256|HAMAP-Rule:MF_01026, ECO:0000256|SAAS:SAAS00385439}.	msb:LJ00_11870, msg:MSMEI_2327, msm:MSMEG_2387	Amino-acid biosynthesis, L-leucine biosynthesis, L-leucine from 3-methyl-2-oxobutanoate: step 2/4. {ECO:0000256|HAMAP-Rule:MF_01026, ECO:0000256|SAAS:SAAS00385511}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0003861 GO:0051539 GO:0009098 GO:0046872 -

GO:0003861

GO:0051539

GO:0009098

GO:0046872

String Network

Link to STRINGS	STRINGS Network
MSMEG_2387

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