MSMEG_5798 MSMEG_5798 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_5798	MSMEG_5798	purM	purM, MSMEG_5798, MSMEI_5644		Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0135	0.57
msm_bicluster_0491	0.54

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R4D8	4531413;	WP_003897216.1, YP_890026.1	ABK69780, AFP42079, AIU10807	IPR010918, IPR016188, IPR004733	COG0150, ENOG4105CXB	EOG61CM1V

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole, ECO:0000256|HAMAP-Rule:MF_00741, ECO:0000256|RuleBase:RU004370, ECO:0000256|SAAS:SAAS00384078}.	msb:LJ00_28670, msg:MSMEI_5644, msm:MSMEG_5798	Purine metabolism, IMP biosynthesis via de novo pathway, 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. {ECO:0000256|HAMAP-Rule:MF_00741, ECO:0000256|RuleBase:RU004371, ECO:0000256|SAAS:SAAS00384047}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0006189 GO:0005524 GO:0005737 GO:0004641 -

GO:0006189

GO:0005524

GO:0005737

GO:0004641

String Network

Link to STRINGS	STRINGS Network
MSMEG_5798

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