G-protein coupled receptor signaling pathway

id: GO:0007186
name: G-protein coupled receptor signaling pathway
namespace: biological_process
type: go
obsolete: False

Description: Any series of molecular signals initiated by an extracellular signal combining with a receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.

Child Functions

idname
GO:0000750pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0000757signal transduction involved in conjugation with mutual genetic exchange
GO:0001789G-protein signaling, coupled to S1P second messenger (sphingosine kinase activating)
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0007200activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0007205activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0007210serotonin receptor signaling pathway
GO:0007211octopamine or tyramine signaling pathway
GO:0007212dopamine receptor signaling pathway
GO:0007213G-protein coupled acetylcholine receptor signaling pathway
GO:0007214gamma-aminobutyric acid signaling pathway
GO:0007216metabotropic glutamate receptor signaling pathway
GO:0007217tachykinin receptor signaling pathway
GO:0007218neuropeptide signaling pathway
GO:0016056rhodopsin mediated signaling pathway
GO:0031583activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway
GO:0031989bombesin receptor signaling pathway
GO:0035588G-protein coupled purinergic receptor signaling pathway
GO:0035625epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0038003opioid receptor signaling pathway
GO:0042699follicle-stimulating hormone signaling pathway
GO:0042700luteinizing hormone signaling pathway
GO:0060183apelin receptor signaling pathway
GO:0070493thrombin receptor signaling pathway
GO:0071875adrenergic receptor signaling pathway
GO:0071926endocannabinoid signaling pathway

Parent Functions

idname
GO:0007166cell surface receptor linked signaling pathway