| COG0021 | Transketolase |
| COG0033 | Phosphoglucomutase |
| COG0036 | Pentose-5-phosphate-3-epimerase |
| COG0057 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase |
| COG0058 | Glucan phosphorylase |
| COG0061 | Predicted sugar kinase |
| COG0063 | Predicted sugar kinase |
| COG0120 | Ribose 5-phosphate isomerase |
| COG0126 | 3-phosphoglycerate kinase |
| COG0129 | Dihydroxyacid dehydratase/phosphogluconate dehydratase |
| COG0148 | Enolase |
| COG0149 | Triosephosphate isomerase |
| COG0153 | Galactokinase |
| COG0158 | Fructose-1,6-bisphosphatase |
| COG0166 | Glucose-6-phosphate isomerase |
| COG0176 | Transaldolase |
| COG0191 | Fructose/tagatose bisphosphate aldolase |
| COG0205 | 6-phosphofructokinase |
| COG0235 | Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases |
| COG0246 | Mannitol-1-phosphate/altronate dehydrogenases |
| COG0269 | 3-hexulose-6-phosphate synthase and related proteins |
| COG0279 | Phosphoheptose isomerase |
| COG0296 | 1,4-alpha-glucan branching enzyme |
| COG0297 | Glycogen synthase |
| COG0362 | 6-phosphogluconate dehydrogenase |
| COG0363 | 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase |
| COG0364 | Glucose-6-phosphate 1-dehydrogenase |
| COG0366 | Glycosidases |
| COG0380 | Trehalose-6-phosphate synthase |
| COG0383 | Alpha-mannosidase |
| COG0395 | ABC-type sugar transport system, permease component |
| COG0406 | Fructose-2,6-bisphosphatase |
| COG0448 | ADP-glucose pyrophosphorylase |
| COG0451 | Nucleoside-diphosphate-sugar epimerases |
| COG0469 | Pyruvate kinase |
| COG0477 | Permeases of the major facilitator superfamily |
| COG0483 | Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family |
| COG0524 | Sugar kinases, ribokinase family |
| COG0537 | Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases |
| COG0574 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase |
| COG0580 | Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) |
| COG0588 | Phosphoglycerate mutase 1 |
| COG0647 | Predicted sugar phosphatases of the HAD superfamily |
| COG0662 | Mannose-6-phosphate isomerase |
| COG0676 | Uncharacterized enzymes related to aldose 1-epimerase |
| COG0696 | Phosphoglyceromutase |
| COG0697 | Permeases of the drug/metabolite transporter (DMT) superfamily |
| COG0698 | Ribose 5-phosphate isomerase RpiB |
| COG0702 | Predicted nucleoside-diphosphate-sugar epimerases |
| COG0726 | Predicted xylanase/chitin deacetylase |
| COG0738 | Fucose permease |
| COG0800 | 2-keto-3-deoxy-6-phosphogluconate aldolase |
| COG0837 | Glucokinase |
| COG1015 | Phosphopentomutase |
| COG1023 | Predicted 6-phosphogluconate dehydrogenase |
| COG1070 | Sugar (pentulose and hexulose) kinases |
| COG1080 | Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) |
| COG1082 | Sugar phosphate isomerases/epimerases |
| COG1086 | Predicted nucleoside-diphosphate sugar epimerases |
| COG1105 | Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) |
| COG1109 | Phosphomannomutase |
| COG1129 | ABC-type sugar transport system, ATPase component |
| COG1134 | ABC-type polysaccharide/polyol phosphate transport system, ATPase component |
| COG1172 | Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components |
| COG1175 | ABC-type sugar transport systems, permease components |
| COG1263 | Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific |
| COG1264 | Phosphotransferase system IIB components |
| COG1299 | Phosphotransferase system, fructose-specific IIC component |
| COG1312 | D-mannonate dehydratase |
| COG1349 | Transcriptional regulators of sugar metabolism |
| COG1363 | Cellulase M and related proteins |
| COG1440 | Phosphotransferase system cellobiose-specific component IIB |
| COG1445 | Phosphotransferase system fructose-specific component IIB |
| COG1447 | Phosphotransferase system cellobiose-specific component IIA |
| COG1449 | Alpha-amylase/alpha-mannosidase |
| COG1455 | Phosphotransferase system cellobiose-specific component IIC |
| COG1472 | Beta-glucosidase-related glycosidases |
| COG1482 | Phosphomannose isomerase |
| COG1486 | Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases |
| COG1494 | Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins |
| COG1501 | Alpha-glucosidases, family 31 of glycosyl hydrolases |
| COG1523 | Type II secretory pathway, pullulanase PulA and related glycosidases |
| COG1548 | Predicted transcriptional regulator/sugar kinase |
| COG1554 | Trehalose and maltose hydrolases (possible phosphorylases) |
| COG1593 | TRAP-type C4-dicarboxylate transport system, large permease component |
| COG1621 | Beta-fructosidases (levanase/invertase) |
| COG1626 | Neutral trehalase |
| COG1638 | TRAP-type C4-dicarboxylate transport system, periplasmic component |
| COG1640 | 4-alpha-glucanotransferase |
| COG1653 | ABC-type sugar transport system, periplasmic component |
| COG1682 | ABC-type polysaccharide/polyol phosphate export systems, permease component |
| COG1762 | Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) |
| COG1803 | Methylglyoxal synthase |
| COG1819 | Glycosyl transferases, related to UDP-glucuronosyltransferase |
| COG1820 | N-acetylglucosamine-6-phosphate deacetylase |
| COG1830 | DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes |
| COG1850 | Ribulose 1,5-bisphosphate carboxylase, large subunit |
| COG1869 | ABC-type ribose transport system, auxiliary component |
| COG1874 | Beta-galactosidase |
| COG1877 | Trehalose-6-phosphatase |
| COG1879 | ABC-type sugar transport system, periplasmic component |
| COG1904 | Glucuronate isomerase |
| COG1925 | Phosphotransferase system, HPr-related proteins |
| COG1929 | Glycerate kinase |
| COG1940 | Transcriptional regulator/sugar kinase |
| COG1980 | Archaeal fructose 1,6-bisphosphatase |
| COG2017 | Galactose mutarotase and related enzymes |
| COG2074 | 2-phosphoglycerate kinase |
| COG2115 | Xylose isomerase |
| COG2133 | Glucose/sorbosone dehydrogenases |
| COG2140 | Thermophilic glucose-6-phosphate isomerase and related metalloenzymes |
| COG2152 | Predicted glycosylase |
| COG2160 | L-arabinose isomerase |
| COG2182 | Maltose-binding periplasmic proteins/domains |
| COG2190 | Phosphotransferase system IIA components |
| COG2211 | Na+/melibiose symporter and related transporters |
| COG2213 | Phosphotransferase system, mannitol-specific IIBC component |
| COG2271 | Sugar phosphate permease |
| COG2273 | Beta-glucanase/Beta-glucan synthetase |
| COG2301 | Citrate lyase beta subunit |
| COG2342 | Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase |
| COG2376 | Dihydroxyacetone kinase |
| COG2379 | Putative glycerate kinase |
| COG2407 | L-fucose isomerase and related proteins |
| COG2513 | PEP phosphonomutase and related enzymes |
| COG2610 | H+/gluconate symporter and related permeases |
| COG2706 | 3-carboxymuconate cyclase |
| COG2721 | Altronate dehydratase |
| COG2723 | Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase |
| COG2730 | Endoglucanase |
| COG2731 | Beta-galactosidase, beta subunit |
| COG2814 | Arabinose efflux permease |
| COG2893 | Phosphotransferase system, mannose/fructose-specific component IIA |
| COG2942 | N-acyl-D-glucosamine 2-epimerase |
| COG2956 | Predicted N-acetylglucosaminyl transferase |
| COG2971 | Predicted N-acetylglucosamine kinase |
| COG3001 | Fructosamine-3-kinase |
| COG3010 | Putative N-acetylmannosamine-6-phosphate epimerase |
| COG3090 | TRAP-type C4-dicarboxylate transport system, small permease component |
| COG3250 | Beta-galactosidase/beta-glucuronidase |
| COG3265 | Gluconate kinase |
| COG3280 | Maltooligosyl trehalose synthase |
| COG3281 | Uncharacterized protein, probably involved in trehalose biosynthesis |
| COG3325 | Chitinase |
| COG3345 | Alpha-galactosidase |
| COG3386 | Gluconolactonase |
| COG3387 | Glucoamylase and related glycosyl hydrolases |
| COG3405 | Endoglucanase Y |
| COG3408 | Glycogen debranching enzyme |
| COG3414 | Phosphotransferase system, galactitol-specific IIB component |
| COG3429 | Glucose-6-P dehydrogenase subunit |
| COG3444 | Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB |
| COG3459 | Cellobiose phosphorylase |
| COG3469 | Chitinase |
| COG3507 | Beta-xylosidase |
| COG3525 | N-acetyl-beta-hexosaminidase |
| COG3534 | Alpha-L-arabinofuranosidase |
| COG3537 | Putative alpha-1,2-mannosidase |
| COG3588 | Fructose-1,6-bisphosphate aldolase |
| COG3594 | Fucose 4-O-acetylase and related acetyltransferases |
| COG3622 | Hydroxypyruvate isomerase |
| COG3623 | Putative L-xylulose-5-phosphate 3-epimerase |
| COG3635 | Predicted phosphoglycerate mutase, AP superfamily |
| COG3661 | Alpha-glucuronidase |
| COG3664 | Beta-xylosidase |
| COG3669 | Alpha-L-fucosidase |
| COG3684 | Tagatose-1,6-bisphosphate aldolase |
| COG3693 | Beta-1,4-xylanase |
| COG3715 | Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC |
| COG3716 | Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID |
| COG3717 | 5-keto 4-deoxyuronate isomerase |
| COG3718 | Uncharacterized enzyme involved in inositol metabolism |
| COG3730 | Phosphotransferase system sorbitol-specific component IIC |
| COG3731 | Phosphotransferase system sorbitol-specific component IIA |
| COG3732 | Phosphotransferase system sorbitol-specific component IIBC |
| COG3734 | 2-keto-3-deoxy-galactonokinase |
| COG3775 | Phosphotransferase system, galactitol-specific IIC component |
| COG3833 | ABC-type maltose transport systems, permease component |
| COG3836 | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
| COG3839 | ABC-type sugar transport systems, ATPase components |
| COG3855 | Uncharacterized protein conserved in bacteria |
| COG3866 | Pectate lyase |
| COG3867 | Arabinogalactan endo-1,4-beta-galactosidase |
| COG3925 | N-terminal domain of the phosphotransferase system fructose-specific component IIB |
| COG3934 | Endo-beta-mannanase |
| COG3936 | Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation |
| COG3957 | Phosphoketolase |
| COG3958 | Transketolase, C-terminal subunit |
| COG3959 | Transketolase, N-terminal subunit |
| COG3961 | Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes |
| COG4101 | Predicted mannose-6-phosphate isomerase |
| COG4124 | Beta-mannanase |
| COG4130 | Predicted sugar epimerase |
| COG4154 | Fucose dissimilation pathway protein FucU |
| COG4193 | Beta- N-acetylglucosaminidase |
| COG4209 | ABC-type polysaccharide transport system, permease component |
| COG4211 | ABC-type glucose/galactose transport system, permease component |
| COG4213 | ABC-type xylose transport system, periplasmic component |
| COG4214 | ABC-type xylose transport system, permease component |
| COG4282 | Protein involved in beta-1,3-glucan synthesis |
| COG4284 | UDP-glucose pyrophosphorylase |
| COG4305 | Endoglucanase C-terminal domain/subunit and related proteins |
| COG4354 | Predicted bile acid beta-glucosidase |
| COG4409 | Neuraminidase (sialidase) |
| COG4421 | Capsular polysaccharide biosynthesis protein |
| COG4464 | Capsular polysaccharide biosynthesis protein |
| COG4468 | Galactose-1-phosphate uridyltransferase |
| COG4573 | Predicted tagatose 6-phosphate kinase |
| COG4580 | Maltoporin (phage lambda and maltose receptor) |
| COG4632 | Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| COG4668 | Mannitol/fructose-specific phosphotransferase system, IIA domain |
| COG4677 | Pectin methylesterase |
| COG4678 | Muramidase (phage lambda lysozyme) |
| COG4692 | Predicted neuraminidase (sialidase) |
| COG4724 | Endo-beta-N-acetylglucosaminidase D |
| COG4806 | L-rhamnose isomerase |
| COG4809 | Archaeal ADP-dependent phosphofructokinase/glucokinase |
| COG4813 | Trehalose utilization protein |
| COG4833 | Predicted glycosyl hydrolase |
| COG4945 | Membrane-anchored protein predicted to be involved in regulation of amylopullulanase |
| COG4975 | Putative glucose uptake permease |
| COG4993 | Glucose dehydrogenase |
| COG5020 | Mannosyltransferase |
| COG5026 | Hexokinase |
| COG5037 | Gluconate transport-inducing protein |
| COG5039 | Exopolysaccharide biosynthesis protein |
| COG5070 | Nucleotide-sugar transporter |
| COG5297 | Cellobiohydrolase A (1,4-beta-cellobiosidase A) |
| COG5309 | Exo-beta-1,3-glucanase |
| COG5371 | Golgi nucleoside diphosphatase |