two-component sensor activity

id: GO:0000155
name: two-component sensor activity
namespace: molecular_function
type: go
obsolete: False

Description: Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

Parent Functions

GO:0004673protein histidine kinase activity
GO:0004871signal transducer activity