THO complex
id: GO:0000347
name: THO complex
namespace: cellular_component
type: go
obsolete: False
Description: The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.
Child Functions
| id | name |
|---|---|
| GO:0000445 | THO complex part of transcription export complex |
| GO:0000446 | nucleoplasmic THO complex |
Parent Functions
| id | name |
|---|---|
| GO:0043234 | protein complex |
| GO:0044428 | nuclear part |
