Group I intron splicing

id: GO:0000372
name: Group I intron splicing
namespace: biological_process
type: go
obsolete: False

Description: The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).

Parent Functions

idname
GO:0000376RNA splicing, via transesterification reactions with guanosine as nucleophile