second spliceosomal transesterification activity

id: GO:0000386
name: second spliceosomal transesterification activity
namespace: molecular_function
type: go
obsolete: False

Description: Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.

Parent Functions