cap-dependent translational initiation

id: GO:0002191
name: cap-dependent translational initiation
namespace: biological_process
type: go
obsolete: False

Description: The process where the \"Cap structure\" (composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins) located at the 5' end of an mRNA molecule, which serves as a \"molecular tag\" that marks the spot where the 40S ribosomal subunit is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.

Parent Functions

idname
GO:0002183cytoplasmic translational initiation