alkylbase DNA N-glycosylase activity
id: GO:0003905
name: alkylbase DNA N-glycosylase activity
namespace: molecular_function
type: go
obsolete: False
Description: Catalysis of the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine. Enzymes with this activity recognize and remove alkylated purines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site.
Child Functions
| id | name |
|---|---|
| GO:0008725 | DNA-3-methyladenine glycosylase I activity |
| GO:0043733 | DNA-3-methyladenine glycosylase III activity |
| GO:0043736 | DNA-3-methyladenine glycosylase IV activity |
| GO:0043916 | DNA-7-methylguanine glycosylase activity |
Parent Functions
| id | name |
|---|---|
| GO:0019104 | DNA N-glycosylase activity |
