Rab geranylgeranyltransferase activity

id: GO:0004663
name: Rab geranylgeranyltransferase activity
namespace: molecular_function
type: go
obsolete: False

Description: Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.

Parent Functions