uracil DNA N-glycosylase activity
id: GO:0004844
name: uracil DNA N-glycosylase activity
namespace: molecular_function
type: go
obsolete: False
Description: Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
Child Functions
id | name |
---|---|
GO:0017065 | single-strand selective uracil DNA N-glycosylase activity |
GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity |
Parent Functions
id | name |
---|---|
GO:0019104 | DNA N-glycosylase activity |