anaphase-promoting complex

id: GO:0005680
name: anaphase-promoting complex
namespace: cellular_component
type: go
obsolete: False

Description: A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.

Parent Functions

idname
GO:0000152nuclear ubiquitin ligase complex
GO:0031461cullin-RING ubiquitin ligase complex