anaphase-promoting complex
id: GO:0005680
name: anaphase-promoting complex
namespace: cellular_component
type: go
obsolete: False
Description: A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
Parent Functions
id | name |
---|---|
GO:0000152 | nuclear ubiquitin ligase complex |
GO:0031461 | cullin-RING ubiquitin ligase complex |