mitochondrial pyruvate dehydrogenase complex
id: GO:0005967
name: mitochondrial pyruvate dehydrogenase complex
namespace: cellular_component
type: go
obsolete: False
Description: Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.
Parent Functions
id | name |
---|---|
GO:0044429 | mitochondrial part |
GO:0045254 | pyruvate dehydrogenase complex |