protein retention in ER lumen

id: GO:0006621
name: protein retention in ER lumen
namespace: biological_process
type: go
obsolete: False

Description: The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.

Parent Functions