negative regulation of gene expression

id: GO:0010629
name: negative regulation of gene expression
namespace: biological_process
type: go
obsolete: False

Description: Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

Child Functions

GO:0008634negative regulation of survival gene product expression
GO:0016458gene silencing
GO:0045814negative regulation of gene expression, epigenetic
GO:0045871negative regulation of rhodopsin gene expression
GO:0045892negative regulation of transcription, DNA-dependent

Parent Functions

GO:0010468regulation of gene expression
GO:0010605negative regulation of macromolecule metabolic process