core-binding factor complex

id: GO:0016513
name: core-binding factor complex
namespace: cellular_component
type: go
obsolete: False

Description: A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.

Parent Functions