SCF ubiquitin ligase complex
id: GO:0019005
name: SCF ubiquitin ligase complex
namespace: cellular_component
type: go
obsolete: False
Description: A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
Child Functions
| id | name |
|---|---|
| GO:0043223 | cytoplasmic SCF ubiquitin ligase complex |
| GO:0043224 | nuclear SCF ubiquitin ligase complex |
Parent Functions
| id | name |
|---|---|
| GO:0031461 | cullin-RING ubiquitin ligase complex |
