desmosome
id: GO:0030057
name: desmosome
namespace: cellular_component
type: go
obsolete: False
Description: A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
Parent Functions
id | name |
---|---|
GO:0005911 | cell-cell junction |
GO:0070161 | anchoring junction |