purine-rich negative regulatory element binding

id: GO:0032422
name: purine-rich negative regulatory element binding
namespace: molecular_function
type: go
obsolete: False

Description: Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.

Parent Functions

GO:0043565sequence-specific DNA binding
GO:0044212transcription regulatory region DNA binding