calcineurin-NFAT signaling pathway
id: GO:0033173
name: calcineurin-NFAT signaling pathway
namespace: biological_process
type: go
obsolete: False
Description: A series of molecular signals that results in activation of transcription by a member of the NFAT protein family as a consequence of NFAT dephosphorylation by activated calcineurin. The signaling is generated by a receptor binding a ligand, followed by activation of phospholipase C and the subsequent release of inositol trisphosphate, which in turn leads to an increase in intracellular calcium ion concentration that mediates the activation of calcineurin.
Parent Functions
id | name |
---|---|
GO:0019722 | calcium-mediated signaling |
GO:0048016 | inositol phosphate-mediated signaling |