CFTR-NHERF-ezrin complex

id: GO:0034662
name: CFTR-NHERF-ezrin complex
namespace: cellular_component
type: go
obsolete: False

Description: A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.

Parent Functions