MH2 domain binding

id: GO:0035500
name: MH2 domain binding
namespace: molecular_function
type: go
obsolete: False

Description: Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.

Parent Functions