MHC class I peptide loading complex

id: GO:0042824
name: MHC class I peptide loading complex
namespace: cellular_component
type: go
obsolete: False

Description: A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.

Parent Functions