nuclear SCF ubiquitin ligase complex
id: GO:0043224
name: nuclear SCF ubiquitin ligase complex
namespace: cellular_component
type: go
obsolete: False
Description: A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
Parent Functions
id | name |
---|---|
GO:0000152 | nuclear ubiquitin ligase complex |
GO:0019005 | SCF ubiquitin ligase complex |