protein targeting to ER
id: GO:0045047
name: protein targeting to ER
namespace: biological_process
type: go
obsolete: False
Description: The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
Child Functions
| id | name |
|---|---|
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane |
| GO:0006620 | posttranslational protein targeting to membrane |
Parent Functions
| id | name |
|---|---|
| GO:0006605 | protein targeting |
| GO:0072599 | establishment of protein localization in endoplasmic reticulum |
