canonical Wnt receptor signaling pathway
id: GO:0060070
name: canonical Wnt receptor signaling pathway
namespace: biological_process
type: go
obsolete: False
Description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Child Functions
| id | name |
|---|---|
| GO:0044328 | canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration |
| GO:0044329 | canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion |
| GO:0044330 | canonical Wnt receptor signaling pathway involved in positive regulation of wound healing |
| GO:0044334 | canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition |
| GO:0044335 | canonical Wnt receptor signaling pathway involved in neural crest cell differentiation |
| GO:0044336 | canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis |
| GO:0044337 | canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis |
| GO:0044338 | canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation |
| GO:0044339 | canonical Wnt receptor signaling pathway involved in osteoblast differentiation |
| GO:0044340 | canonical Wnt receptor signaling pathway involved in regulation of cell proliferation |
| GO:0060823 | canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation |
| GO:0060901 | regulation of hair cycle by canonical Wnt receptor signaling pathway |
| GO:0061290 | canonical Wnt receptor signaling pathway involved in metanephric kidney development |
| GO:0061292 | canonical Wnt receptor signaling pathway involved in mesonephros development |
| GO:0061316 | canonical Wnt receptor signaling pathway involved in heart development |
Parent Functions
| id | name |
|---|---|
| GO:0016055 | Wnt receptor signaling pathway |
