canonical Wnt receptor signaling pathway involved in heart development
id: GO:0061316
name: canonical Wnt receptor signaling pathway involved in heart development
namespace: biological_process
type: go
obsolete: False
Description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Child Functions
id | name |
---|---|
GO:0003136 | negative regulation of heart induction by canonical Wnt receptor signaling pathway |
GO:0003267 | canonical Wnt receptor signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation |
GO:0061310 | canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development |
GO:0061315 | canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation |
GO:0061317 | canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment |
GO:0061324 | canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation |
Parent Functions
id | name |
---|---|
GO:0003306 | Wnt receptor signaling pathway involved in heart development |
GO:0060070 | canonical Wnt receptor signaling pathway |