interferon regulatory factor complex
id: GO:0097071
name: interferon regulatory factor complex
namespace: cellular_component
type: go
obsolete: False
Description: A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.
Child Functions
id | name |
---|---|
GO:0097072 | interferon regulatory factor 3 complex |
GO:0097073 | interferon regulatory factor 5 complex |
GO:0097074 | interferon regulatory factor 7 complex |
GO:0097075 | interferon regulatory factor 3-interferon regulatory factor 7 complex |
GO:0097085 | interferon regulatory factor 3-interferon regulatory factor 5 complex |
Parent Functions
id | name |
---|---|
GO:0043234 | protein complex |