interferon regulatory factor complex

id: GO:0097071
name: interferon regulatory factor complex
namespace: cellular_component
type: go
obsolete: False

Description: A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.

Child Functions

idname
GO:0097072interferon regulatory factor 3 complex
GO:0097073interferon regulatory factor 5 complex
GO:0097074interferon regulatory factor 7 complex
GO:0097075interferon regulatory factor 3-interferon regulatory factor 7 complex
GO:0097085interferon regulatory factor 3-interferon regulatory factor 5 complex

Parent Functions

idname
GO:0043234protein complex