|  |  | protein polyubiquitinationubiquitin-protein ligase activityprotein bindingcytoplasmcytosolzinc ion bindingcytoplasmic side of plasma membraneprotein ubiquitinationligase activityCD40 signaling pathwayCD40 receptor complexpositive regulation of I-kappaB kinase/NF-kappaB signalingubiquitin bindingmetal ion bindingT cell receptor signaling pathwaypositive regulation of NF-kappaB transcription factor activitynegative regulation of necroptotic processLUBAC complexprotein linear polyubiquitination
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