PITA_11 megaCluster: 3 Residual: 0.18 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_11	3	0.18	15	0	0.949352	0

Members

Displaying 1 - 36 of 36

100504377 predicted gene, 20199 Details for - - predicted gene, 20199 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504377 Tuberculist Genomic Region	12642 cholesterol 25-hydroxylase Details for - - cholesterol 25-hydroxylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12642 Tuberculist Genomic Region
13660 EH-domain containing 1 Details for - - EH-domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13660 Tuberculist Genomic Region	13713 ELK3, member of ETS oncogene family Details for - - ELK3, member of ETS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13713 Tuberculist Genomic Region
14260 formin 1 Details for RP23-248J10.1 - formin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14260 Tuberculist Genomic Region	15251 hypoxia inducible factor 1, alpha subunit Details for - - hypoxia inducible factor 1, alpha subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15251 Tuberculist Genomic Region
15937 immediate early response 3 Details for - - immediate early response 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15937 Tuberculist Genomic Region	16798 large tumor suppressor Details for - - large tumor suppressor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16798 Tuberculist Genomic Region
18081 ninjurin 1 Details for - - ninjurin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18081 Tuberculist Genomic Region	19225 prostaglandin-endoperoxide synthase 2 Details for - - prostaglandin-endoperoxide synthase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19225 Tuberculist Genomic Region
20525 solute carrier family 2 (facilitated glucose transporter), member 1 Details for RP23-344D2.2 - solute carrier family 2 (facilitated glucose transporter), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20525 Tuberculist Genomic Region	226691 expressed sequence AI607873 Details for - - expressed sequence AI607873 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226691 Tuberculist Genomic Region
23983 poly(rC) binding protein 1 Details for - - poly(rC) binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23983 Tuberculist Genomic Region	244871 zinc finger CCCH type containing 12C Details for - - zinc finger CCCH type containing 12C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244871 Tuberculist Genomic Region
26374 ring finger and WD repeat domain 2 Details for mCG_124354 - ring finger and WD repeat domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26374 Tuberculist Genomic Region	26896 mediator complex subunit 14 Details for RP24-392J24.6 - mediator complex subunit 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26896 Tuberculist Genomic Region
320207 phosphoinositide-3-kinase, regulatory subunit 5, p101 Details for RP23-432M23.2 - phosphoinositide-3-kinase, regulatory subunit 5, p101 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320207 Tuberculist Genomic Region	338365 solute carrier family 41, member 2 Details for - - solute carrier family 41, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 338365 Tuberculist Genomic Region
56228 ubiquitin-conjugating enzyme E2J 1 Details for RP23-12I24.8 - ubiquitin-conjugating enzyme E2J 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56228 Tuberculist Genomic Region	622976 predicted gene 6377 Details for RP23-252O5.3 - predicted gene 6377 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 622976 Tuberculist Genomic Region
67154 metadherin Details for - - metadherin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67154 Tuberculist Genomic Region	67712 solute carrier family 25, member 37 Details for - - solute carrier family 25, member 37 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67712 Tuberculist Genomic Region
68142 INO80 homolog (S. cerevisiae) Details for RP23-46P4.10-001 - INO80 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68142 Tuberculist Genomic Region	68473 MOB kinase activator 1B Details for - - MOB kinase activator 1B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68473 Tuberculist Genomic Region
71436 fibronectin leucine rich transmembrane protein 3 Details for RP23-388J20.1 - fibronectin leucine rich transmembrane protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71436 Tuberculist Genomic Region	73914 interleukin-1 receptor-associated kinase 3 Details for - - interleukin-1 receptor-associated kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73914 Tuberculist Genomic Region
74277 cysteine-rich hydrophobic domain 2 Details for - - cysteine-rich hydrophobic domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74277 Tuberculist Genomic Region	77036 RIKEN cDNA 1700109H08 gene Details for - - RIKEN cDNA 1700109H08 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77036 Tuberculist Genomic Region
791367 predicted gene 10099 Details for - - predicted gene 10099 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 791367 Tuberculist Genomic Region	791405 predicted gene 10002 Details for - - predicted gene 10002 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 791405 Tuberculist Genomic Region
100434 solute carrier family 44, member 1 Details for RP23-20E10.4 - solute carrier family 44, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100434 Tuberculist Genomic Region	109711 actinin, alpha 1 Details for - - actinin, alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109711 Tuberculist Genomic Region
17342 microphthalmia-associated transcription factor Details for - - microphthalmia-associated transcription factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17342 Tuberculist Genomic Region	18578 phosphodiesterase 4B, cAMP specific Details for RP23-57D24.1 - phosphodiesterase 4B, cAMP specific GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18578 Tuberculist Genomic Region
19271 protein tyrosine phosphatase, receptor type, J Details for RP24-113P16.2 - protein tyrosine phosphatase, receptor type, J GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19271 Tuberculist Genomic Region	226562 proline-rich coiled-coil 2C Details for - - proline-rich coiled-coil 2C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226562 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_CBF_01_M01079	0.30303	0.000058

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000015	TRANAAAAAAAA	NA	28	YYCCCCNCCCCC	SP1_MA0079.2, V$SP1_03_M02281, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q2_01_M00933, V$CKROX_Q2_M01175, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$ZNF219_01_M01122, V$MAZR_01_M00491, V$SP1_Q6_M00196, V$KLF15_Q2_M01714, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$MAZ_Q6_M00649, V$ZBP89_Q4_M01816, V$MZF1_01_M00083, V$MZF1_02_M00084, V$MZF1_Q5_M01733, V$CHCH_01_M00986, V$GC_01_M00255, V$KROX_Q6_M00982, V$EGR1_Q6_M01873, V$ZFP410_04_M02936, Zfp281.2, Zfp410.1, Sp4.1, Bcl6b.2, Klf7.1, Egr1.1, Zfp740.1, Ascl2.2, Smad3.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.29	RCGGCG	NA	1.31	CCCCGNCG

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.5	TTATCN	NA	NA	0.66	TAATTTKT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-214, mmu-miR-761	0.923077	0.00000025

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-291a-5p	0.555556	0.000000862

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