PITA_18 megaCluster: 9 Residual: 0.20

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_18	9	0.20	15	0	0.935461	0

Members

Displaying 1 - 40 of 40

TFBS DB TF

TFs	percTargets	pValue
SP1_MA0079.2, V_SP1_03_M02281	1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000023	CCCCGCCCCYC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$KLF7_03_M02773, V$SP1_Q6_01_M00931, V$SP1_02_M01303, V$GKLF_02_M01588, V$GC_01_M00255, V$SP1_03_M02281, V$ZFP281_01_M01597, V$ZFP281_04_M02831, V$SP4_03_M02810, V$CKROX_Q2_M01175, V$ZBP89_Q4_M01816, V$SP1_01_M00008, V$MAZR_01_M00491, V$CACD_01_M01113, V$KROX_Q6_M00982, V$EGR1_Q6_M01873, V$EGR1_06_M02744, V$SMAD4_04_M02898, V$MAZ_Q6_M00649, V$UF1H3BETA_Q6_M01068, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$E2F3_Q6_M02089, V$EKLF_Q5_M01874, V$ZNF219_01_M01122, V$WT1_Q6_01_M02036, V$BCL6B_04_M02844, V$SP2_01_M01783, V$ZFP740_03_M02834, V$KLF15_Q2_M01714, V$ZFP410_04_M02936, V$ETF_Q6_M00695, V$CACCCBINDINGFACTOR_Q6_M00721, V$FKLF_Q5_M01837, V$CACBINDINGPROTEIN_Q6_M00720, Klf7.1, Zfp281.2, Sp4.1, Egr1.1, Smad3.1, Bcl6b.2, Zfp740.1, Zfp410.1, Ascl2.2, Zif268.1, Sox13.2, Sp4.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, Zfp740_C2H2_DBD_monomeric_10_1	0.0000039	AAAAMANAAAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.42	ACCGCG	NA	1.45	TTTCGCGG	V$E2F_Q6_M00427, V$E2F1_Q6_01_M00940, V$E2F1_Q6_M00431, V$E2F_Q4_M00426, V$E2F1_Q4_M00430, V$E2F_Q3_01_M00918, V$E2F_Q4_02_M00939

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.49	GCGCGC	NA	NA	0.67	GTAGCCNA	mmu-mir-138-1-3p	7mer_m8

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

108062 cleavage stimulation factor, 3' pre-RNA subunit 2 Details for RP23-182N4.2 - cleavage stimulation factor, 3' pre-RNA subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108062 Tuberculist Genomic Region	108156 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Details for - - methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108156 Tuberculist Genomic Region
12190 breast cancer 2 Details for - - breast cancer 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12190 Tuberculist Genomic Region	14251 flotillin 1 Details for - - flotillin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14251 Tuberculist Genomic Region
16443 intersectin 1 (SH3 domain protein 1A) Details for - - intersectin 1 (SH3 domain protein 1A) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16443 Tuberculist Genomic Region	16498 potassium voltage-gated channel, shaker-related subfamily, beta member 2 Details for RP23-421E12.12-005 - potassium voltage-gated channel, shaker-related subfamily, beta member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16498 Tuberculist Genomic Region
17218 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) Details for - - minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17218 Tuberculist Genomic Region	18744 praja1, RING-H2 motif containing Details for RP23-414J22.4 - praja1, RING-H2 motif containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18744 Tuberculist Genomic Region
18974 polymerase (DNA directed), epsilon 2 (p59 subunit) Details for - - polymerase (DNA directed), epsilon 2 (p59 subunit) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18974 Tuberculist Genomic Region	19076 DNA primase, p58 subunit Details for - - DNA primase, p58 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19076 Tuberculist Genomic Region
19360 RAD50 homolog (S. cerevisiae) Details for RP23-239O19.3 - RAD50 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19360 Tuberculist Genomic Region	19714 REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) Details for - - REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19714 Tuberculist Genomic Region
209131 sorting nexin family member 30 Details for RP23-451K12.1 - sorting nexin family member 30 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209131 Tuberculist Genomic Region	211389 sulfite oxidase Details for - - sulfite oxidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211389 Tuberculist Genomic Region
223921 achalasia, adrenocortical insufficiency, alacrimia Details for - - achalasia, adrenocortical insufficiency, alacrimia GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223921 Tuberculist Genomic Region	226432 importin 9 Details for - - importin 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226432 Tuberculist Genomic Region
240168 RAS, guanyl releasing protein 3 Details for - - RAS, guanyl releasing protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240168 Tuberculist Genomic Region	320088 RIKEN cDNA C030034L19 gene Details for - - RIKEN cDNA C030034L19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320088 Tuberculist Genomic Region
330361 GC-rich sequence DNA binding factor 2 Details for - - GC-rich sequence DNA binding factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330361 Tuberculist Genomic Region	52665 enoyl Coenzyme A hydratase domain containing 1 Details for - - enoyl Coenzyme A hydratase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52665 Tuberculist Genomic Region
56187 Rab geranylgeranyl transferase, a subunit Details for - - Rab geranylgeranyl transferase, a subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56187 Tuberculist Genomic Region	56207 ubiquitin carboxyl-terminal esterase L5 Details for - - ubiquitin carboxyl-terminal esterase L5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56207 Tuberculist Genomic Region
60534 Fanconi anemia, complementation group G Details for RP23-124L1.6 - Fanconi anemia, complementation group G GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60534 Tuberculist Genomic Region	66179 2-oxoglutarate and iron-dependent oxygenase domain containing 3 Details for RP23-349B15.2 - 2-oxoglutarate and iron-dependent oxygenase domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66179 Tuberculist Genomic Region
68041 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) Details for RP23-130J1.1 - Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68041 Tuberculist Genomic Region	68145 Ewing tumor-associated antigen 1 Details for RP23-353E13.3 - Ewing tumor-associated antigen 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68145 Tuberculist Genomic Region
68845 PIH1 domain containing 1 Details for - - PIH1 domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68845 Tuberculist Genomic Region	69662 RIKEN cDNA 2310061I04 gene Details for RP24-180B11.5 - RIKEN cDNA 2310061I04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69662 Tuberculist Genomic Region
72749 tonsoku-like, DNA repair protein Details for - - tonsoku-like, DNA repair protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72749 Tuberculist Genomic Region	75146 transmembrane protein 180 Details for - - transmembrane protein 180 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75146 Tuberculist Genomic Region
76467 methionine sulfoxide reductase B2 Details for RP23-34E4.2 - methionine sulfoxide reductase B2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76467 Tuberculist Genomic Region	76967 RIKEN cDNA 2700049A03 gene Details for - - RIKEN cDNA 2700049A03 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76967 Tuberculist Genomic Region
77065 integrator complex subunit 7 Details for - - integrator complex subunit 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77065 Tuberculist Genomic Region	77744 bora, aurora kinase A activator Details for - - bora, aurora kinase A activator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77744 Tuberculist Genomic Region
97487 CKLF-like MARVEL transmembrane domain containing 4 Details for - - CKLF-like MARVEL transmembrane domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97487 Tuberculist Genomic Region	98732 RAB3 GTPase activating protein subunit 2 Details for - - RAB3 GTPase activating protein subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98732 Tuberculist Genomic Region
99138 START domain containing 7 Details for RP23-206D14.5 - START domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99138 Tuberculist Genomic Region	218639 ADP-ribosylation factor-like 15 Details for - - ADP-ribosylation factor-like 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218639 Tuberculist Genomic Region
333433 glycerol-3-phosphate dehydrogenase 1-like Details for - - glycerol-3-phosphate dehydrogenase 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 333433 Tuberculist Genomic Region	66881 prenylcysteine oxidase 1 Details for - - prenylcysteine oxidase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66881 Tuberculist Genomic Region

Summary

Members

Details for RP23-182N4.2 - cleavage stimulation factor, 3' pre-RNA subunit 2

Details for - - methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

Details for - - breast cancer 2

Details for - - flotillin 1

Details for - - intersectin 1 (SH3 domain protein 1A)

Details for RP23-421E12.12-005 - potassium voltage-gated channel, shaker-related subfamily, beta member 2

Details for - - minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)

Details for RP23-414J22.4 - praja1, RING-H2 motif containing

Details for - - polymerase (DNA directed), epsilon 2 (p59 subunit)

Details for - - DNA primase, p58 subunit

Details for RP23-239O19.3 - RAD50 homolog (S. cerevisiae)

Details for - - REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)

Details for RP23-451K12.1 - sorting nexin family member 30

Details for - - sulfite oxidase

Details for - - achalasia, adrenocortical insufficiency, alacrimia

Details for - - importin 9

Details for - - RAS, guanyl releasing protein 3

Details for - - RIKEN cDNA C030034L19 gene

Details for - - GC-rich sequence DNA binding factor 2

Details for - - enoyl Coenzyme A hydratase domain containing 1

Details for - - Rab geranylgeranyl transferase, a subunit

Details for - - ubiquitin carboxyl-terminal esterase L5

Details for RP23-124L1.6 - Fanconi anemia, complementation group G

Details for RP23-349B15.2 - 2-oxoglutarate and iron-dependent oxygenase domain containing 3

Details for RP23-130J1.1 - Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

Details for RP23-353E13.3 - Ewing tumor-associated antigen 1

Details for - - PIH1 domain containing 1

Details for RP24-180B11.5 - RIKEN cDNA 2310061I04 gene

Details for - - tonsoku-like, DNA repair protein

Details for - - transmembrane protein 180

Details for RP23-34E4.2 - methionine sulfoxide reductase B2

Details for - - RIKEN cDNA 2700049A03 gene

Details for - - integrator complex subunit 7

Details for - - bora, aurora kinase A activator

Details for - - CKLF-like MARVEL transmembrane domain containing 4

Details for - - RAB3 GTPase activating protein subunit 2

Details for RP23-206D14.5 - START domain containing 7

Details for - - ADP-ribosylation factor-like 15

Details for - - glycerol-3-phosphate dehydrogenase 1-like

Details for - - prenylcysteine oxidase 1

GO Terms

3p UTR PITA