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- guanyl-nucleotide exchange factor activity
- Rho guanyl-nucleotide exchange factor activity
- calcium ion binding
- protein binding
- plasma membrane
- coated pit
- endocytosis
- small GTPase mediated signal transduction
- membrane
- kinase activator activity
- lamellipodium
- cell junction
- endocytic vesicle
- protein complex scaffold
- regulation of Rho protein signal transduction
- intracellular signal transduction
- positive regulation of phosphorylation
- cell projection
- neuron projection
- positive regulation of catalytic activity
- negative regulation of neuron apoptotic process
- synapse
- metal ion binding
- positive regulation of protein kinase B signaling
- proline-rich region binding
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