PITA_205 megaCluster: 3 Residual: 0.18 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_205	3	0.18	15	0	0.929792	0

Members

Displaying 1 - 23 of 23

108673 coiled-coil domain containing 86 Details for MNCb-4327 - coiled-coil domain containing 86 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108673 Tuberculist Genomic Region	108960 interleukin-1 receptor-associated kinase 2 Details for - - interleukin-1 receptor-associated kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108960 Tuberculist Genomic Region
121021 chondroitin sulfate proteoglycan 4 Details for - - chondroitin sulfate proteoglycan 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 121021 Tuberculist Genomic Region	12363 caspase 4, apoptosis-related cysteine peptidase Details for - - caspase 4, apoptosis-related cysteine peptidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12363 Tuberculist Genomic Region
12642 cholesterol 25-hydroxylase Details for - - cholesterol 25-hydroxylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12642 Tuberculist Genomic Region	14081 acyl-CoA synthetase long-chain family member 1 Details for - - acyl-CoA synthetase long-chain family member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14081 Tuberculist Genomic Region
15950 interferon activated gene 203 Details for - - interferon activated gene 203 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15950 Tuberculist Genomic Region	16181 interleukin 1 receptor antagonist Details for RP23-218B17.2 - interleukin 1 receptor antagonist GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16181 Tuberculist Genomic Region
16402 integrin alpha 5 (fibronectin receptor alpha) Details for - - integrin alpha 5 (fibronectin receptor alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16402 Tuberculist Genomic Region	170736 parvin, beta Details for - - parvin, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170736 Tuberculist Genomic Region
170829 translocating chain-associating membrane protein 2 Details for - - translocating chain-associating membrane protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170829 Tuberculist Genomic Region	17936 Ngfi-A binding protein 1 Details for - - Ngfi-A binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17936 Tuberculist Genomic Region
18227 nuclear receptor subfamily 4, group A, member 2 Details for RP23-271B15.1 - nuclear receptor subfamily 4, group A, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18227 Tuberculist Genomic Region	19271 protein tyrosine phosphatase, receptor type, J Details for RP24-113P16.2 - protein tyrosine phosphatase, receptor type, J GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19271 Tuberculist Genomic Region
20442 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 Details for - - ST3 beta-galactoside alpha-2,3-sialyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20442 Tuberculist Genomic Region	22169 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial Details for - - cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22169 Tuberculist Genomic Region
269966 nucleoporin 98 Details for - - nucleoporin 98 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269966 Tuberculist Genomic Region	276950 schlafen 8 Details for RP23-392I13.9 - schlafen 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 276950 Tuberculist Genomic Region
54004 diaphanous homolog 2 (Drosophila) Details for - - diaphanous homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54004 Tuberculist Genomic Region	54711 pleiomorphic adenoma gene-like 2 Details for RP23-192G18.4 - pleiomorphic adenoma gene-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54711 Tuberculist Genomic Region
58185 radical S-adenosyl methionine domain containing 2 Details for - - radical S-adenosyl methionine domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58185 Tuberculist Genomic Region	73914 interleukin-1 receptor-associated kinase 3 Details for - - interleukin-1 receptor-associated kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73914 Tuberculist Genomic Region
20656 superoxide dismutase 2, mitochondrial Details for - - superoxide dismutase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20656 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
SP1_MA0079.2, V_SP1_03_M02281	1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
39	CTCTCYCWCCA	NA	590	GCCCCGCCCCC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, Zfx_MA0146.1, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_03_M02281, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP2_01_M01783, V$UF1H3BETA_Q6_M01068, V$ZFP281_01_M01597, V$KLF7_03_M02773, V$SP1_01_M00008, V$GKLF_02_M01588, V$SP1_02_M01303, V$MAZR_01_M00491, V$SP4_03_M02810, V$KROX_Q6_M00982, V$ZFP281_04_M02831, V$ZNF219_01_M01122, Klf7.1, Sp4.1, Zfp281.2, Zfp410.1, Bcl6b.2, Smad3.1, Egr1.1, Ascl2.2, Zfp740.1, Sp4.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.2	GCGGTG	NA	1.43	CGCGGTGA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.75	ATCCSTCG	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-5108	0.428571	0.0000171

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