PITA_216 megaCluster: 10 Residual: 0.21

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_216 10 0.21 15 0 0.910703 0

Members

Displaying 1 - 39 of 39
109232 saccharopine dehydrogenase (putative)

Details for - - saccharopine dehydrogenase (putative)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 109232

Tuberculist Genomic Region

100201 transmembrane protein 64

Details for RP23-23D11.2 - transmembrane protein 64

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100201

Tuberculist Genomic Region

102334 ankyrin repeat domain 10

Details for - - ankyrin repeat domain 10

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 102334

Tuberculist Genomic Region

106952 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

Details for - - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 106952

Tuberculist Genomic Region

11306 ATP-binding cassette, sub-family B (MDR/TAP), member 7

Details for RP23-202N14.1 - ATP-binding cassette, sub-family B (MDR/TAP), member 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11306

Tuberculist Genomic Region

114863 proline synthetase co-transcribed

Details for - - proline synthetase co-transcribed

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 114863

Tuberculist Genomic Region

13006 structural maintenance of chromosomes 3

Details for - - structural maintenance of chromosomes 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13006

Tuberculist Genomic Region

13478 dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)

Details for - - dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13478

Tuberculist Genomic Region

140483 histamine N-methyltransferase

Details for RP23-263E15.1 - histamine N-methyltransferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 140483

Tuberculist Genomic Region

14218 SH3 and PX domains 2A

Details for - - SH3 and PX domains 2A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14218

Tuberculist Genomic Region

170439 ELOVL family member 6, elongation of long chain fatty acids (yeast)

Details for - - ELOVL family member 6, elongation of long chain fatty acids (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170439

Tuberculist Genomic Region

18968 polymerase (DNA directed), alpha 1

Details for RP23-53K18.2 - polymerase (DNA directed), alpha 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18968

Tuberculist Genomic Region

207818 small cell adhesion glycoprotein

Details for - - small cell adhesion glycoprotein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 207818

Tuberculist Genomic Region

20933 mediator complex subunit 22

Details for RP23-414L19.3 - mediator complex subunit 22

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20933

Tuberculist Genomic Region

211896 DEP domain containing 7

Details for RP24-297H17.8 - DEP domain containing 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 211896

Tuberculist Genomic Region

217653 MIS18 binding protein 1

Details for - - MIS18 binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217653

Tuberculist Genomic Region

22154 tubulin, beta 5 class I

Details for RP24-180B11.2 - tubulin, beta 5 class I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22154

Tuberculist Genomic Region

233724 transmembrane protein 41B

Details for - - transmembrane protein 41B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 233724

Tuberculist Genomic Region

236792 membrane magnesium transporter 1

Details for - - membrane magnesium transporter 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 236792

Tuberculist Genomic Region

241633 ATPase, class I, type 8B, member 4

Details for RP23-460B5.1 - ATPase, class I, type 8B, member 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 241633

Tuberculist Genomic Region

245474 dyskeratosis congenita 1, dyskerin

Details for RP23-62O13.1 - dyskeratosis congenita 1, dyskerin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245474

Tuberculist Genomic Region

28042 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

Details for - - ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 28042

Tuberculist Genomic Region

328186 predicted gene 10336

Details for - - predicted gene 10336

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 328186

Tuberculist Genomic Region

381680 neurexophilin and PC-esterase domain family, member 5

Details for - - neurexophilin and PC-esterase domain family, member 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 381680

Tuberculist Genomic Region

52538 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)

Details for - - acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52538

Tuberculist Genomic Region

57750 WD repeat domain 12

Details for MNCb-5414 - WD repeat domain 12

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 57750

Tuberculist Genomic Region

66310 dpy-30 homolog (C. elegans)

Details for - - dpy-30 homolog (C. elegans)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66310

Tuberculist Genomic Region

66531 COX assembly mitochondrial protein 2

Details for - - COX assembly mitochondrial protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66531

Tuberculist Genomic Region

67276 exoribonuclease 1

Details for - - exoribonuclease 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67276

Tuberculist Genomic Region

67618 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Details for - - aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67618

Tuberculist Genomic Region

68092 nuclear cap binding protein subunit 2

Details for - - nuclear cap binding protein subunit 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68092

Tuberculist Genomic Region

69048 solute carrier family 30 (zinc transporter), member 5

Details for - - solute carrier family 30 (zinc transporter), member 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69048

Tuberculist Genomic Region

69723 RPA interacting protein

Details for DN-393H17.1 - RPA interacting protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69723

Tuberculist Genomic Region

70123 RIKEN cDNA 2210013O21 gene

Details for - - RIKEN cDNA 2210013O21 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70123

Tuberculist Genomic Region

72544 exosome component 6

Details for - - exosome component 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72544

Tuberculist Genomic Region

72722 family with sequence similarity 98, member A

Details for - - family with sequence similarity 98, member A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72722

Tuberculist Genomic Region

72787 NDC1 transmembrane nucleoporin

Details for RP23-392J14.4 - NDC1 transmembrane nucleoporin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72787

Tuberculist Genomic Region

110173 mannosidase, beta A, lysosomal

Details for - - mannosidase, beta A, lysosomal

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110173

Tuberculist Genomic Region

72503 RIKEN cDNA 2610507B11 gene

Details for RP23-185A18.9 - RIKEN cDNA 2610507B11 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72503

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
V_GATA1_06_M00347 0.131579 0.000041

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.000000000000003 AAAAARAAAAAA NA 0.28 GNGGGCGGGKCC Klf4_MA0039.2, SP1_MA0079.2, Egr1_MA0162.1, SP1_MA0079.1, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$GC_01_M00255, V$SP4_03_M02810, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$KLF7_03_M02773, V$EGR1_Q6_M01873, V$SP2_01_M01783, V$GKLF_02_M01588, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$SP1_02_M01303, V$SP1_01_M00008, V$SMAD4_04_M02898, V$EGR_Q6_M00807, V$SP1_03_M02281, V$E2F3_Q6_M02089, V$ZBP89_Q4_M01816, V$ZFP740_03_M02834, V$SP4_04_M02914, V$WT1_Q6_01_M02036, V$EGR1_02_M01972, V$NGFIC_01_M00244, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$ZFP281_01_M01597, V$EGR1_01_M00243, V$MAZR_01_M00491, V$ZFP281_04_M02831, V$UF1H3BETA_Q6_M01068, V$EGR2_01_M00246, V$CKROX_Q2_M01175, V$WT1_Q6_M01118, V$CACD_01_M01113, V$EGR3_01_M00245, V$MAZ_Q6_M00649, V$ZNF219_01_M01122, V$CACBINDINGPROTEIN_Q6_M00720, V$BCL6B_04_M02844, V$KLF7_04_M02877, V$E2F_Q2_M00803, Sp4.1, Klf7.1, Egr1.1, Smad3.1, Zif268.1, Zfp740.1, Sp4.2, Zfp281.2, Klf7.2, Bcl6b.2, Zfp410.1, Ascl2.2, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, KLF13_C2H2_full_monomeric_18_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1, EGR2_C2H2_full_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1, EGR4_C2H2_DBD_monomeric_16_2, Egr3_C2H2_DBD_monomeric_15_1, EGR2_C2H2_DBD_monomeric_11_1, EGR1_C2H2_full_monomeric_14_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.33 ACGGCG NA 1.26 CCGCGGGA V$RNF96_01_M01199

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.7 ANNACTAA NA NA NA NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
NA

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