PITA_70 megaCluster: 11 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_70	11	0.22	15	0	0.898565	0

Members

Displaying 1 - 30 of 30

15312 aldolase C, fructose-bisphosphate Details for - - aldolase C, fructose-bisphosphate GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11676 Tuberculist Genomic Region	16907 high mobility group nucleosomal binding domain 1 Details for - - high mobility group nucleosomal binding domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15312 Tuberculist Genomic Region
18453 lamin B2 Details for - - lamin B2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16907 Tuberculist Genomic Region	19769 prolyl 4-hydroxylase, beta polypeptide Details for RP23-84C12.2 - prolyl 4-hydroxylase, beta polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18453 Tuberculist Genomic Region
20341 Ras-like without CAAX 1 Details for - - Ras-like without CAAX 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19769 Tuberculist Genomic Region	22027 selenium binding protein 1 Details for - - selenium binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20341 Tuberculist Genomic Region
319322 heat shock protein 90, beta (Grp94), member 1 Details for - - heat shock protein 90, beta (Grp94), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22027 Tuberculist Genomic Region	399101 splicing factor 3b, subunit 2 Details for - - splicing factor 3b, subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 319322 Tuberculist Genomic Region
66234 small nucleolar RNA host gene (non-protein coding) 3 Details for - - small nucleolar RNA host gene (non-protein coding) 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 399101 Tuberculist Genomic Region	66471 sterol-C4-methyl oxidase-like Details for - - sterol-C4-methyl oxidase-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66234 Tuberculist Genomic Region
66591 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E Details for - - acidic (leucine-rich) nuclear phosphoprotein 32 family, member E GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66471 Tuberculist Genomic Region	67151 MAD2L1 binding protein Details for - - MAD2L1 binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66591 Tuberculist Genomic Region
67247 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 Details for - - proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67151 Tuberculist Genomic Region	67755 mitochondrial amidoxime reducing component 2 Details for - - mitochondrial amidoxime reducing component 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67247 Tuberculist Genomic Region
70385 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 Details for - - DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67755 Tuberculist Genomic Region	72391 spindle apparatus coiled-coil protein 1 Details for RP23-329D21.1 - spindle apparatus coiled-coil protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70385 Tuberculist Genomic Region
76547 cyclin-dependent kinase inhibitor 3 Details for - - cyclin-dependent kinase inhibitor 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72391 Tuberculist Genomic Region	76863 transmembrane protein 101 Details for RP23-167N11.1 - transmembrane protein 101 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76547 Tuberculist Genomic Region
97122 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) Details for - - DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76863 Tuberculist Genomic Region	98415 histone cluster 2, H4 Details for - - histone cluster 2, H4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97122 Tuberculist Genomic Region
195434 nuclear casein kinase and cyclin-dependent kinase substrate 1 Details for - - nuclear casein kinase and cyclin-dependent kinase substrate 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98415 Tuberculist Genomic Region	230908 UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast) Details for - - UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 195434 Tuberculist Genomic Region
236539 TAR DNA binding protein Details for RP23-331P21.5 - TAR DNA binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230908 Tuberculist Genomic Region	433637 3-phosphoglycerate dehydrogenase Details for - - 3-phosphoglycerate dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236539 Tuberculist Genomic Region
54405 predicted gene 5547 Details for - - predicted gene 5547 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 433637 Tuberculist Genomic Region	66447 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 Details for RP23-43O20.5 - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54405 Tuberculist Genomic Region
66870 microsomal glutathione S-transferase 3 Details for - - microsomal glutathione S-transferase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66447 Tuberculist Genomic Region	72657 serpine1 mRNA binding protein 1 Details for - - serpine1 mRNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66870 Tuberculist Genomic Region
77022 RIKEN cDNA 2700094K13 gene Details for - - RIKEN cDNA 2700094K13 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72657 Tuberculist Genomic Region	Details for - - NDC80 homolog, kinetochore complex component pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77022 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_AP1_Q2_01_M00924	0.37037	0.0000211

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.02	TNTTTTTNTTT	Foxj3_forkhead_DBD_dimeric_13_1	550	SCNCCACCYCC	SP1_MA0079.2, V$SP1SP3_Q4_M01219, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$UF1H3BETA_Q6_M01068, V$GC_01_M00255, V$SP1_Q6_01_M00931, V$ZBP89_Q4_M01816, V$MAZR_01_M00491, V$ZNF219_01_M01122, V$CACD_01_M01113, V$ETF_Q6_M00695, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$WT1_Q6_01_M02036, V$KLF15_Q2_M01714, V$ZFP740_03_M02834, Zfp281.2, Zfp740.1, Sp4.1, Egr1.1, Bcl6b.2

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.28	AACGCG	NA	1.52	NAGGCGCG	V$E2F_Q2_M00803, E2F2.1, Sp4.2, E2F3.1, Bcl6b.2, Zfp410.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.71	GCGAGT	NA	NA	0.73	GCTNNCAT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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